Special

FBgn0034433 @ dm6

Biotype
protein_coding
Gene Symbol
EndoB
Description
The gene Endophilin B is referred to in FlyBase by the symbol DmelEndoB (CG9834, FBgn0034433). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2R:19307447..19310665. Its molecular function is described by: lysophosphatidic acid acyltransferase activity; phospholipid binding. It is involved in the biological process described with: clathrin-dependent endocytosis involved in vitellogenesis; membrane organization; vitellogenesis; plasma membrane tubulation. 12 alleles are reported. The phenotypes of these alleles manifest in: yolk granule; eye; mesothoracic tergum; oocyte. The phenotypic classes of alleles include: decreased fecundity; partially lethal - majority die; visible; viable; lethal - all die during larval stage; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr2R:19307447-19310665:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
36
chr2R:19309663-19309698
-
41.02
100
2
Intron Retention
117
chr2R:19309699-19309815
-
4.97
100
0
Intron Retention
79
chr2R:19309584-19309662
-
7.88
84.17
0
Intron Retention
579
chr2R:19308814-19309392
-
9.78
45.47
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000097033 SH3GLB1 1-to-2
Human hg38 ENSG00000148341 SH3GLB2 1-to-2
Human hg19 ENSG00000097033 SH3GLB1 1-to-2
Human hg19 ENSG00000148341 SH3GLB2 1-to-2
Mouse mm10 ENSMUSG00000026860 Sh3glb2 1-to-2
Mouse mm10 ENSMUSG00000037062 Sh3glb1 1-to-2
Mouse mm9 ENSMUSG00000026860 Sh3glb2 1-to-2
Mouse mm9 ENSMUSG00000037062 Sh3glb1 1-to-2
Rat rn6 ENSRNOG00000012957 Sh3glb1 1-to-2
Rat rn6 ENSRNOG00000017295 Sh3glb2 1-to-2
Cow bosTau6 ENSBTAG00000010626 SH3GLB2 1-to-2
Cow bosTau6 ENSBTAG00000031171 SH3GLB1 1-to-2
Chicken galGal4 ENSGALG00000006284 SH3GLB1 1-to-2
Chicken galGal3 ENSGALG00000006284 SHLB1_CHICK 1-to-2
Zebrafish danRer10 ENSDARG00000008983 sh3glb2a 1-to-4
Zebrafish danRer10 ENSDARG00000010956 sh3glb1b 1-to-4
Zebrafish danRer10 ENSDARG00000035470 sh3glb2b 1-to-4
Zebrafish danRer10 ENSDARG00000045294 sh3glb1a 1-to-4