Special

FBgn0034451 @ dm6

Biotype
protein_coding
Gene Symbol
TBCB
Description
The gene tubulin-binding cofactor B is referred to in FlyBase by the symbol DmelTBCB (CG11242, FBgn0034451). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:19485494..19486837. Its molecular function is described by: microtubule plus-end binding. It is involved in the biological process described with: establishment of mitotic spindle orientation; establishment of apical/basal cell polarity; oocyte axis specification; cytoplasmic microtubule organization; nuclear migration. 10 alleles are reported. The phenotypes of these alleles manifest in: egg chamber; female reproductive system; female-specific anatomical entity; germline cell; stem cell. The phenotypic classes of alleles include: phenotype; lethal - all die before end of prepupal stage; increased mortality during development; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr2R:19485494-19486837:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)


Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000105254 TBCB 1-to-2
Human hg38 ENSG00000135837 CEP350 1-to-2
Human hg19 ENSG00000105254 TBCB 1-to-2
Human hg19 ENSG00000135837 CEP350 1-to-2
Mouse mm10 ENSMUSG00000006095 Tbcb 1-to-2
Mouse mm10 ENSMUSG00000033671 Cep350 1-to-2
Mouse mm9 ENSMUSG00000006095 Tbcb 1-to-2
Mouse mm9 ENSMUSG00000033671 Cep350 1-to-2
Rat rn6 ENSRNOG00000020781 Tbcb 1-to-2
Rat rn6 ENSRNOG00000045655 LOC103690005 1-to-2
Cow bosTau6 ENSBTAG00000008082 CEP350 1-to-2
Cow bosTau6 ENSBTAG00000015004 TBCB 1-to-2
Chicken galGal4 ENSGALG00000003955 CEP350 1-to-1
Chicken galGal3 ENSGALG00000003955 CEP350 1-to-1
Zebrafish danRer10 ENSDARG00000058000 cep350 1-to-2
Zebrafish danRer10 ENSDARG00000068404 tbcb 1-to-2