FBgn0034451 @ dm6
Biotype
protein_coding
Gene Symbol
TBCB
Description
The gene tubulin-binding cofactor B is referred to in FlyBase by the symbol DmelTBCB (CG11242, FBgn0034451). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:19485494..19486837. Its molecular function is described by: microtubule plus-end binding. It is involved in the biological process described with: establishment of mitotic spindle orientation; establishment of apical/basal cell polarity; oocyte axis specification; cytoplasmic microtubule organization; nuclear migration. 10 alleles are reported. The phenotypes of these alleles manifest in: egg chamber; female reproductive system; female-specific anatomical entity; germline cell; stem cell. The phenotypic classes of alleles include: phenotype; lethal - all die before end of prepupal stage; increased mortality during development; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr2R:19485494-19486837:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000105254 | TBCB | 1-to-2 |
Human | hg38 | ENSG00000135837 | CEP350 | 1-to-2 |
Human | hg19 | ENSG00000105254 | TBCB | 1-to-2 |
Human | hg19 | ENSG00000135837 | CEP350 | 1-to-2 |
Mouse | mm10 | ENSMUSG00000006095 | Tbcb | 1-to-2 |
Mouse | mm10 | ENSMUSG00000033671 | Cep350 | 1-to-2 |
Mouse | mm9 | ENSMUSG00000006095 | Tbcb | 1-to-2 |
Mouse | mm9 | ENSMUSG00000033671 | Cep350 | 1-to-2 |
Rat | rn6 | ENSRNOG00000020781 | Tbcb | 1-to-2 |
Rat | rn6 | ENSRNOG00000045655 | LOC103690005 | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000008082 | CEP350 | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000015004 | TBCB | 1-to-2 |
Chicken | galGal4 | ENSGALG00000003955 | CEP350 | 1-to-1 |
Chicken | galGal3 | ENSGALG00000003955 | CEP350 | 1-to-1 |
Zebrafish | danRer10 | ENSDARG00000058000 | cep350 | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000068404 | tbcb | 1-to-2 |