FBgn0040339 @ dm6
Biotype
protein_coding
Gene Symbol
MED22
Description
The gene Mediator complex subunit 22 is referred to in FlyBase by the symbol DmelMED22 (CG3034, FBgn0040339). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:928139..928860. Its molecular function is described by: transcription coregulator activity; protein binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; regulation of transcription from RNA polymerase II promoter involved in spermatogenesis; mitotic cell cycle. 8 alleles are reported. The phenotypes of these alleles manifest in: neuroblast; spermatocyte; nucleolus. The phenotypic classes of alleles include: neuroanatomy defective; meiotic cell cycle defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages.
Coordinates
chrX:928139-928860:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000148297 | MED22 | 2-to-1 |
| Human | hg19 | ENSG00000148297 | MED22 | 2-to-1 |
| Mouse | mm10 | ENSMUSG00000015776 | Med22 | 2-to-1 |
| Mouse | mm9 | ENSMUSG00000015776 | Med22 | 2-to-1 |
| Rat | rn6 | ENSRNOG00000005059 | Med22 | 2-to-2 |
| Rat | rn6 | ENSRNOG00000049749 | LOC100911917 | 2-to-2 |
| Cow | bosTau6 | ENSBTAG00000011556 | MED22 | 2-to-1 |
| Chicken | galGal4 | ENSGALG00000003204 | MED22 | 2-to-1 |
| Chicken | galGal3 | ENSGALG00000003204 | MED22_CHICK | 2-to-1 |
| Zebrafish | danRer10 | ENSDARG00000014148 | med22 | 2-to-1 |