Special

FBgn0051481 @ dm6

Biotype
protein_coding
Gene Symbol
pb
Description
The gene proboscipedia is referred to in FlyBase by the symbol Dmelpb (CG31481, FBgn0051481). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:6707800..6742063. Its molecular function is described by: RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with: specification of segmental identity, maxillary segment; proboscis development; positive regulation of transcription by RNA polymerase II; specification of segmental identity, labial segment. 98 alleles are reported. The phenotypes of these alleles manifest in: primordium; stage 7 embryo; early extended germ band embryo; embryonic midgut chamber 1; prothoracic ventral intersegmental muscle. The phenotypic classes of alleles include: lethal; visible; lethal - all die before end of pupal stage; short lived; some die during pupal stage; wild-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.
Coordinates
chr3R:6707800-6742063:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Intron Retention
993
chr3R:6740175-6741167
-
14.54
100
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000105996 HOXA2 1-to-2
Human hg38 ENSG00000173917 HOXB2 1-to-2
Human hg19 ENSG00000105996 HOXA2 1-to-2
Human hg19 ENSG00000173917 HOXB2 1-to-2
Mouse mm10 ENSMUSG00000014704 Hoxa2 1-to-2
Mouse mm10 ENSMUSG00000075588 Hoxb2 1-to-2
Mouse mm9 ENSMUSG00000014704 Hoxa2 1-to-2
Mouse mm9 ENSMUSG00000075588 Hoxb2 1-to-2
Rat rn6 ENSRNOG00000005968 Hoxa2 1-to-3
Rat rn6 ENSRNOG00000008365 Hoxb2 1-to-3
Rat rn6 ENSRNOG00000059600 Hoxa2 1-to-3
Cow bosTau6 ENSBTAG00000008138 HOXA2 1-to-2
Cow bosTau6 ENSBTAG00000009979 HOXB2 1-to-2
Chicken galGal4 ENSGALG00000025774 HOXB2 1-to-2
Zebrafish danRer10 ENSDARG00000000175 hoxb2a 1-to-2
Zebrafish danRer10 ENSDARG00000023031 hoxa2b 1-to-2