FBgn0085447 @ dm6
Biotype
protein_coding
Gene Symbol
sif
Description
The gene still life is referred to in FlyBase by the symbol Dmelsif (CG34418, FBgn0085447). It is a protein_coding_gene from Dmel. It has 14 annotated transcripts and 14 polypeptides (12 unique). Gene sequence location is 3L:5657913..5749599. Its molecular function is described by: Rac guanyl-nucleotide exchange factor activity. It is involved in the biological process described with 11 unique terms, many of which group under: sensory perception of light stimulus; sensory system development; activation of GTPase activity; regulation of molecular function; sensory perception. 26 alleles are reported. The phenotypes of these alleles manifest in: retinal pigment cell; eye; mesothoracic tergum; chaeta; interommatidial bristle. The phenotypic classes of alleles include: cell number defective; behavior defective; locomotor behavior defective; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
Coordinates
chr3L:5657913-5749599:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000146426 | TIAM2 | 1-to-2 |
| Human | hg38 | ENSG00000156299 | TIAM1 | 1-to-2 |
| Human | hg19 | ENSG00000146426 | TIAM2 | 1-to-2 |
| Human | hg19 | ENSG00000156299 | TIAM1 | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000002489 | Tiam1 | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000023800 | Tiam2 | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000002489 | Tiam1 | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000023800 | Tiam2 | 1-to-2 |
| Rat | rn6 | ENSRNOG00000016728 | Tiam2 | 1-to-2 |
| Rat | rn6 | ENSRNOG00000021569 | Tiam1 | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000010047 | TIAM2 | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000017839 | TIAM1 | 1-to-2 |
| Chicken | galGal4 | ENSGALG00000015842 | TIAM1 | 1-to-2 |
| Chicken | galGal3 | ENSGALG00000015842 | TIAM1 | 1-to-2 |
| Zebrafish | danRer10 | ENSDARG00000025920 | tiam1b | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000078430 | tiam1a | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000087780 | tiam2a | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000098233 | TIAM2 (2 of 2) | 1-to-4 |