DmeALTA0004985-3/3 @ dm6
Alternative 3'ss
Gene
FBgn0263219 | Dscam4
Description
The gene Down syndrome cell adhesion molecule 4 is referred to in FlyBase by the symbol DmelDscam4 (CG42330, FBgn0263219). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 3L:8238647..8282398. Its molecular function is described by: cell-cell adhesion mediator activity; identical protein binding. It is involved in the biological process described with: homophilic cell adhesion via plasma membrane adhesion molecules; axon guidance; cell adhesion; dendrite self-avoidance. 17 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
Coordinates
chr3L:8279894-8280409:+
Coord C1 exon
chr3L:8279894-8279966
Coord A exon
chr3L:8280260-8280328
Coord C2 exon
chr3L:8280329-8280409
Length
69 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGCT
5' ss Score
6.77
3' ss Seq
ATCCGTACTAAACTTTTTAGAAT
3' ss Score
4.93
Exon sequences
Seq C1 exon
TCCAAGGAACCGGAGTACACCAAAGTGCGGCGAAAAGTGGGTCGCCTCAGGGATCCTCATTCAGAGAGCCAAG
Seq A exon
AATCGGACAATCCAGGTTCAACAGATTCCGAAGTTAGGAAAATCCTAACGCTTCACATCCCAATTACAG
Seq C2 exon
AATATGACACACTCGGCTCCGAGTCCGACAATGATGTGTCTGCGCGAGCTCTAAACTCGGCCAAGTATCGAGCACAACGTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263219-38-37,38-36,38-35-3/3
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.946
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
FBpp0305766
Main Skipping Isoform:
FBpp0289117
Other Inclusion Isoforms:
FBpp0305767
Other Skipping Isoforms:
FBpp0289118, FBpp0289119
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAAGGAACCGGAGTACACC
R:
ACGTTGTGCTCGATACTTGGC
Band lengths:
153-222
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)