DmeINT0019567 @ dm6
Intron Retention
Gene
FBgn0263219 | Dscam4
Description
The gene Down syndrome cell adhesion molecule 4 is referred to in FlyBase by the symbol DmelDscam4 (CG42330, FBgn0263219). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 3L:8238647..8282398. Its molecular function is described by: cell-cell adhesion mediator activity; identical protein binding. It is involved in the biological process described with: homophilic cell adhesion via plasma membrane adhesion molecules; axon guidance; cell adhesion; dendrite self-avoidance. 17 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
Coordinates
chr3L:8279894-8280409:+
Coord C1 exon
chr3L:8279894-8279966
Coord A exon
chr3L:8279967-8280328
Coord C2 exon
chr3L:8280329-8280409
Length
362 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGCT
5' ss Score
6.77
3' ss Seq
GCTTCACATCCCAATTACAGAAT
3' ss Score
6.01
Exon sequences
Seq C1 exon
TCCAAGGAACCGGAGTACACCAAAGTGCGGCGAAAAGTGGGTCGCCTCAGGGATCCTCATTCAGAGAGCCAAG
Seq A exon
GTAGCTATGAGATGGTCTTAACGTTCATCCCTCCTGTCATTCGTACAAGCCCCAGTCCTACCGCCAATCCACTGATTCCATCTAGCCGTAAGCCAAATTGAATCATCGCTTGTCATAATCGCACCCCATCCCATCCCATCCAGATGCCAATCCAAACGATCCCCCGTACCCTTGGTTTAACCCATCTTTTTCTCATTGCTCTCAACGTTTTTCTCCACACACATTCGTACATCATCTCGATAAAAACCAACAAACAACGTACAAATCCATCGAATCCGTACTAAACTTTTTAGAATCGGACAATCCAGGTTCAACAGATTCCGAAGTTAGGAAAATCCTAACGCTTCACATCCCAATTACAG
Seq C2 exon
AATATGACACACTCGGCTCCGAGTCCGACAATGATGTGTCTGCGCGAGCTCTAAACTCGGCCAAGTATCGAGCACAACGTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263219:FBtr0299839:29
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.972
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0289117
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0289118, FBpp0289119
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)