DmeALTA0005448-1/2 @ dm6
Alternative 3'ss
Gene
FBgn0264562 | Hr4
Description
The gene Hormone receptor 4 is referred to in FlyBase by the symbol DmelHr4 (CG43934, FBgn0264562). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (8 unique). Gene sequence location is X:1941940..2007956. Its molecular function is described by: steroid hormone receptor activity; nuclear receptor activity; zinc ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with 7 unique terms, many of which group under: cellular response to chemical stimulus; regulation of developmental process; negative regulation of RNA metabolic process; prepupal development; negative regulation of cellular response to alcohol. 73 alleles are reported. The phenotypes of these alleles manifest in: embryo; eye; somatic cell; ommatidium; head. The phenotypic classes of alleles include: size defective; lethal - all die before end of pupal stage; phenotype; some die during P-stage.
Coordinates
chrX:2000771-2002353:+
Coord C1 exon
chrX:2000771-2002159
Coord A exon
NA
Coord C2 exon
chrX:2002235-2002353
Length
0 bp
Sequences
Splice sites
5' ss Seq
AAGGTACGT
5' ss Score
10.75
3' ss Seq
TCGTTTTGTAAATCCAGCAGAAG
3' ss Score
1.8
Exon sequences
Seq C1 exon
ACTGTGCAACATCGGCGATTCCATAGTCCACAAGCTGGTGTCGTGGACAAAAAAGTTGCCCTTCTACCTGGAGATCCCGGTGGAGATACATACCAAACTACTGACGGACAAGTGGCACGAGATCCTTATCCTGACCACGGCCGCCTACCAGGCGTTGCATGGCAAGCGGCGTGGCGAGGGAGGAGGCAGCAGGCATGGTTCGCCGGCGTCAACGCCACTGAGCACGCCCACTGGTACGCCGTTGAGCACACCGATACCCTCGCCCGCCCAGCCACTGCACAAGGACGACCCGGAGTTTGTCAGCGAGGTGAACTCGCACCTGAGCACACTGCAAACCTGCTTGACCACGCTAATGGGCCAGCCGATAGCGATGGAGCAGCTGAAGCTGGACGTCGGGCACATGGTGGACAAGATGACCCAGATCACCATCATGTTCCGGCGAATCAAGCTCAAGATGGAGGAGTACGTCTGCCTGAAGGTTTACATACTGCTAAACAAAG
Seq A exon
NA
Seq C2 exon
AAGTGGAACTGGAGAGCATCCAGGAGCGGTACGTCCAGGTGCTGCGCTCCTACCTGCAAAACTCCTCGCCGCAGAATCCGCAGGCGAGGCTCAGTGAACTGCTCTCCCACATACCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0264562-19-21,19-20-1/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.588 A=NA C2=0.059
Domain overlap (PFAM):
C1:
PF0010425=Hormone_recep=PU(75.6=39.4)
A:
NA
C2:
PF0010425=Hormone_recep=FE(16.0=100)
Main Inclusion Isoform:
FBpp0305531
Main Skipping Isoform:
FBpp0305535
Other Inclusion Isoforms:
FBpp0305530, FBpp0305533
Other Skipping Isoforms:
FBpp0305529, FBpp0305532, FBpp0305534, FBpp0305536, FBpp0305537
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGAGTACGTCTGCCTGAAGG
R:
GGAGTTTTGCAGGTAGGAGCG
Band lengths:
107-110
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)