DmeALTA0005913-1/4 @ dm6
Alternative 3'ss
Gene
FBgn0085434 | NaCP60E
Description
The gene Na channel protein 60E is referred to in FlyBase by the symbol DmelNaCP60E (CG34405, FBgn0085434). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (9 unique). Gene sequence location is 2R:24891614..24921677. Its molecular function is described by: voltage-gated sodium channel activity; voltage-gated cation channel activity; cation channel activity. It is involved in the biological process described with: sodium ion transmembrane transport; neuronal action potential; olfactory behavior; membrane depolarization during action potential; sodium ion transport. 40 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: behavior defective; viable; smell perception defective; chemical resistant. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 06-12 and 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
Coordinates
chr2R:24915281-24915831:+
Coord C1 exon
chr2R:24915281-24915462
Coord A exon
NA
Coord C2 exon
chr2R:24915731-24915831
Length
0 bp
Sequences
Splice sites
5' ss Seq
ACGGTAGTT
5' ss Score
3.98
3' ss Seq
AACTTAAGCCCTATTTCTAGCAA
3' ss Score
1.1
Exon sequences
Seq C1 exon
GTGAGTCGTCGAGGCACTGCCTGCTCCAGTCGAGCCTCGTCTCGAAAATCGTCGCGTGCCTCGGATGCATCCGATCTTAGCGAACTAGCTGGGCCTTGGTTGAACCTGCCTCTGATGCTCGTCTCAGGTGCCGACGAAGTAGTCAAGGATATAAAACAGCAAAACGACGAGCTGGGCAAACG
Seq A exon
NA
Seq C2 exon
CAAATCCTCTTGTATCTCCCTAAACTATGAGTCCCTGCTCGCAGACATGGTCACTGCCGTTCTCAGAAGTGGCTCGCAGCCTAGTGGCTTGAATTATCTAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0085434-40-38,40-37,40-36,40-35-1/4
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.461 A=NA C2=0.200
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
FBpp0300664
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAACAGCAAAACGACGAGCTG
R:
CTTCTGAGAACGGCAGTGACC
Band lengths:
98-110
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)