DmeALTA0005939-1/2 @ dm6
Alternative 3'ss
Gene
FBgn0259111 | Ndae1
Description
The gene Na[+]-driven anion exchanger 1 is referred to in FlyBase by the symbol DmelNdae1 (CG42253, FBgn0259111). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (10 unique). Gene sequence location is 2L:7223328..7249343. Its molecular function is described by: inorganic anion exchanger activity; anion:anion antiporter activity; sodium:bicarbonate symporter activity. It is involved in the biological process described with 6 unique terms, many of which group under: transport; establishment of localization; ion transmembrane transport; localization; inorganic ion transmembrane transport. 16 alleles are reported. The phenotype of these alleles manifest in: imaginal disc. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 18-24 hour embryonic stages.
Coordinates
chr2L:7230889-7234997:-
Coord C1 exon
chr2L:7234527-7234997
Coord A exon
NA
Coord C2 exon
chr2L:7230889-7231126
Length
0 bp
Sequences
Splice sites
5' ss Seq
AAAGTGAGT
5' ss Score
8.4
3' ss Seq
AAACCTGTCATCGATCACAGAGG
3' ss Score
5.09
Exon sequences
Seq C1 exon
TGACTCCGCCGGCACAGCGAGTTCAATTCATACTTGGCGAGGATGTGGACGATGGCACACACGTATCGCATCCCCTGTTTTCGGAAATGGGGATGCTGGTCAAGGAGGGCGACGAGATCGAGTGGAAGGAGACAGCGCGATGGATCAAATTCGAGGAGGATGTGGAGGAGGGTGGCAATCGATGGTCGAAGCCGCACGTGGCCACGCTCTCCCTGCACTCCCTGTTCGAGCTGCGTCGCCTGCTGGTCAATGGCAGCGTGATGCTGGACATGGAGGCCCAAAATCTGGAGGTGATGGCCGATCTCGTGTGCGATCACATGGTCAGTGCGGGAACATTGCCGCCCGGTGTAAAGGATAAGGTCAAGGACGCGCTCCTGCGACGACATCGGCATCAGCACGAGTATGCCAAAAAGACGCGACTGCCAATTATTCGATCCCTGGCCGATATGCGCAATCACTCGTCATCAAAAA
Seq A exon
NA
Seq C2 exon
AGGACATGGTCAAGAGTCCCAGTAACCAGTCGATGGCCAGGCCAGGAAGCGGAACGGAACTCAGCGAGCAGCAGCACAAGGGCAACACCCACTTCATGAGGAAGATACCGCCGGGCGCGGAGGCCAGCAACATTCTCGTGGGCGAGGTTGATTTCCTGGAGCGCACCCTGTCCTGTTTCATCCGTCTGAGCCAGGCGGTCGTCCTGGGCGATCTCACCGAGGTGCCAGTGCCCACAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0259111-13-15,13-14-1/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.326 A=NA C2=0.514
Domain overlap (PFAM):
C1:
PF075658=Band_3_cyto=PU(38.7=65.8)
A:
NA
C2:
PF075658=Band_3_cyto=FE(31.6=100)
Main Inclusion Isoform:
FBpp0304050
Main Skipping Isoform:
FBpp0288814
Other Inclusion Isoforms:
FBpp0304051, FBpp0304052, FBpp0304053
Other Skipping Isoforms:
FBpp0288812, FBpp0288813, FBpp0304048, FBpp0304049, FBpp0304054
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATAAGGTCAAGGACGCGCTC
R:
TGGGACTCTTGACCATGTCCT
Band lengths:
139-196
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)