DmeALTA0006839-2/5 @ dm6
Alternative 3'ss
Gene
FBgn0035050 | ST6Gal
Description
The gene Sialyltransferase is referred to in FlyBase by the symbol DmelSiaT (CG4871, FBgn0035050). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:24691422..24694386. Its molecular function is described by: sialyltransferase activity; beta-galactoside alpha-2,6-sialyltransferase activity. It is involved in the biological process described with: oligosaccharide metabolic process; neuromuscular junction development; protein glycosylation. 12 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuromuscular junction; wing; NMJ bouton. The phenotypic classes of alleles include: phenotype; fertile; paralytic; neurophysiology defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed during early larval stages, during late pupal stages.
Coordinates
chr2R:24693287-24694386:-
Coord C1 exon
chr2R:24694271-24694386
Coord A exon
chr2R:24693348-24693469
Coord C2 exon
chr2R:24693287-24693347
Length
122 bp
Sequences
Splice sites
5' ss Seq
TCGGTACGT
5' ss Score
10.06
3' ss Seq
TTGAGCCCTCGTTCGACCAGCGT
3' ss Score
4.85
Exon sequences
Seq C1 exon
AGATACGTTTCGGCTGGCGAAAGGGAAAGTTCGAACTGCGGACGCGTCGCCGGAAAATCCTTCGCTTTTCCGGCTGCTTTTCCGAGTTTTGCGGGCTGCATGTGAACGCACTGTCG
Seq A exon
CGTATTATGAGTGGAGAATGAGGCAAGTGACACGCGCATCGTCGGGTCAAAGTCAGGCCCTCCTTTCATGCCTCATTATCGCCGTGTGCGCCGCATTAATAATTCAATCTGGGCATATCCAG
Seq C2 exon
GGTGTGAAAGCTCAGCCGGGACGCGAACCCGGCGAGGTGAATTCGCGGCAGCCCGGCAACG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0035050-0-4,0-3,0-2,0-1,0-0-2/5
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.250
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
NO
Main Inclusion Isoform:
FBpp0072347
Main Skipping Isoform:
FBpp0072346
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGATACGTTTCGGCTGGCGAA
R:
GGGCTGCCGCGAATTCAC
Band lengths:
170-292
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)