DmeALTA0007003-2/2 @ dm6

FBgn0020378 | Sp1

The gene Sp1 is referred to in FlyBase by the symbol DmelSp1 (CG1343, FBgn0020378). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is X:9729648..9756369. Its molecular function is described by: sequence-specific DNA binding; transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; imaginal disc-derived leg morphogenesis. 16 alleles are reported. The phenotypes of these alleles manifest in: cell cluster organ; portion of tissue; anlage; first segment of antenna; presumptive tarsal segment 4. The phenotypic classes of alleles include: visible; viable; size defective; lethal; homeotic; cell shape defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.

• DmeALTA0007003-1/2