Special

FBgn0020378 @ dm6

Biotype
protein_coding
Gene Symbol
Sp1
Description
The gene Sp1 is referred to in FlyBase by the symbol DmelSp1 (CG1343, FBgn0020378). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is X:9729648..9756369. Its molecular function is described by: sequence-specific DNA binding; transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; imaginal disc-derived leg morphogenesis. 16 alleles are reported. The phenotypes of these alleles manifest in: cell cluster organ; portion of tissue; anlage; first segment of antenna; presumptive tarsal segment 4. The phenotypic classes of alleles include: visible; viable; size defective; lethal; homeotic; cell shape defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.
Coordinates
chrX:9729648-9756369:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
0
NA
+
41.36
58.81
0
Alternative 3'ss
15
chrX:9753541-9753555
+
58.64
58.81
0
Alternative 5'ss
0
NA
+
14.52
37.22
0
Alternative 5'ss
13
chrX:9729871-9729883
+
85.48
37.22
0
Intron Retention
429
chrX:9729871-9730299
+
80.04
76.77
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000164651 SP8 1-to-4
Human hg38 ENSG00000170374 SP7 1-to-4
Human hg38 ENSG00000189120 SP6 1-to-4
Human hg38 ENSG00000217236 SP9 1-to-4
Human hg19 ENSG00000164651 SP8 1-to-4
Human hg19 ENSG00000170374 SP7 1-to-4
Human hg19 ENSG00000189120 SP6 1-to-4
Human hg19 ENSG00000217236 SP9 1-to-4
Mouse mm10 ENSMUSG00000038560 Sp6 1-to-4
Mouse mm10 ENSMUSG00000048562 Sp8 1-to-4
Mouse mm10 ENSMUSG00000060284 Sp7 1-to-4
Mouse mm10 ENSMUSG00000068859 Sp9 1-to-4
Mouse mm9 ENSMUSG00000038560 Sp6 1-to-4
Mouse mm9 ENSMUSG00000048562 Sp8 1-to-4
Mouse mm9 ENSMUSG00000060284 Sp7 1-to-4
Mouse mm9 ENSMUSG00000068859 Sp9 1-to-4
Rat rn6 ENSRNOG00000005943 Sp8 1-to-2
Rat rn6 ENSRNOG00000028187 Sp9 1-to-2
Cow bosTau6 ENSBTAG00000001825 SP6 1-to-4
Cow bosTau6 ENSBTAG00000002604 SP8 1-to-4
Cow bosTau6 ENSBTAG00000014949 SP9 1-to-4
Cow bosTau6 ENSBTAG00000033292 SP7 1-to-4
Zebrafish danRer10 ENSDARG00000011870 sp8a 1-to-5
Zebrafish danRer10 ENSDARG00000019516 sp7 1-to-5
Zebrafish danRer10 ENSDARG00000056666 sp8b 1-to-5
Zebrafish danRer10 ENSDARG00000099374 sp9 1-to-5
Zebrafish danRer10 ENSDARG00000099880 SP6 1-to-5