Special

DmeALTD0006797-1/2 @ dm6

Alternative 5'ss

Gene
Description
The gene Sp1 is referred to in FlyBase by the symbol DmelSp1 (CG1343, FBgn0020378). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is X:9729648..9756369. Its molecular function is described by: sequence-specific DNA binding; transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; imaginal disc-derived leg morphogenesis. 16 alleles are reported. The phenotypes of these alleles manifest in: cell cluster organ; portion of tissue; anlage; first segment of antenna; presumptive tarsal segment 4. The phenotypic classes of alleles include: visible; viable; size defective; lethal; homeotic; cell shape defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.
Coordinates
chrX:9729770-9730677:+
Coord C1 exon
chrX:9729770-9729870
Coord A exon
NA
Coord C2 exon
chrX:9730300-9730677
Length
0 bp
Sequences
Splice sites
5' ss Seq
ACTGTGTGC
5' ss Score
-1.29
3' ss Seq
TTTTTCCCTTACTCTCCAAGATC
3' ss Score
6.76
Exon sequences
Seq C1 exon
ATAAACATAAAAACAAACAAGCAAATAAATAAACAATAAACCAACAAGCAAACAAACAAACATAAACAAGCCAACAAGCAGCCAAGCTAAACAAAACAACT
Seq A exon
NA
Seq C2 exon
ATCAGTGAGCCTGGCCTGCAACAATAGTCGCAACAAAGAAAAAAGTAGTTGAGTTGAGCAAGAAGAAAAGAATAGAAAATCGAACCCTAAACCCAAGTGGCCGCAAAACAAAGCAGAAGCAAAACAGACAGCATCATTGTGCGCCTCAAATTGACATCAGCAGCAGCAGCAGCAGCCGCAGCAGCAACGACAACTGCCACTGCCACTGCAGCAGCAGCAACATCAGCAGCAGCAGGAGACGCAGCAGGAACATCCACAGCAACCATGTTAACGGACATGACACCGACCGCCGGTCAGCTCTACGGATCCCAGATTCCGGCCATGGGCATGAACATCAGCAATATCGCCACACACTTGCAGAAGCCACAAGTTAATCCG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0020378-0-1,1-1-1/2
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact

5' UTR

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=NA C2=0.789
Domain overlap (PFAM):

C1:
NA
A:
NA
C2:
NO


Main Inclusion Isoform:
NA


Main Skipping Isoform:
FBpp0303753


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
FBpp0271862
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCAACAAGCAAACAAACAAACA
R:
CGACTATTGTTGCAGGCCAGG
Band lengths:
92-105
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)