Special

DmeALTA0007526-1/5 @ dm6

Alternative 3'ss

Gene
FBgn0000014 | abd-A
Description
The gene abdominal A is referred to in FlyBase by the symbol Dmelabd-A (CG10325, FBgn0000014). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 3R:16807214..16830049. Its molecular function is described by: DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; cis-regulatory region sequence-specific DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with 26 unique terms, many of which group under: reproduction; developmental process involved in reproduction; imaginal disc development; muscle tissue development; pole cell migration. 128 alleles are reported. The phenotypes of these alleles manifest in: germline cell; male reproductive system; A1-7 ventral oblique muscle; eo-type sensillum; dorsal thoracic disc. The phenotypic classes of alleles include: increased cell death; phenotype; lethal - all die before end of prepupal stage; cell number defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed during late larval stages, during early pupal stages.
Coordinates
chr3R:16827739-16830049:-
Coord C1 exon
chr3R:16828921-16830049
Coord A exon
NA
Coord C2 exon
chr3R:16827739-16827897
Length
0 bp
Sequences
Splice sites
5' ss Seq
AAGGTAACA
5' ss Score
8.92
3' ss Seq
CCCGAATTCGTCATCTGCAGCAG
3' ss Score
5.25
Exon sequences
Seq C1 exon
GGTTCTCGCCTCTCCGTTCCAGACTTCGATAGTTCTACCTGCAAAGTGTTTTATGACATTTTAAACAAAGTAATTAAAGCAAAACGTTGGGAGAAAGCATTTCTCCGGCCACACACACACTCACGCACTTGAGAAGTCGTTAAAAGCCGCAGGAAACTCACTCTGCCATAAAAATACAAGAGTGCCATTAAAAAAGATCGCGCGCCTATAAATCACACGTACGAAATCCCGCCGGCACGACGTCCATTCGAATTTCCGCGTAATTGATGACCGCATTTTAATTGCTTTTACAACAAATAAAAGATACACACACCCCAAACACACACATGCGACACACACACTTGTGCCACAGCTGCAAATACAACGCAACCCGAGACCATATGCAAATTTAACAAATTTCGTTGTGAATTCGCCAGCTTCGAGCGAAAAAAGTAACAGAAACAGAAAAGCTGCAAATACAAGCTGCTCGCCAAAAGTTCGCTAGAGAAAACTTGAGAAAG
Seq A exon
NA
Seq C2 exon
CAGTTGCCGCCGCCCTAGCCGCCGCCGCCGCCTCTGCATCCGCCAGCGTTTCAGCCAGCAGCAGCAGCAACAACAACAGCAGCAACACGATCGCTGGAAGCAACACAAGCAACACCAACAATAGCAGCAGCAGTCCAAGCAGCAGCAGCAACAACAACA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0000014-0-5,0-3,0-2,0-1,0-0-1/5
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact

Protein isoform when splice site is used (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=NA C2=0.100
Domain overlap (PFAM):

C1:
NA
A:
NA
C2:
NO


Main Inclusion Isoform:
FBpp0289712


Main Skipping Isoform:
FBpp0082829


Other Inclusion Isoforms:
FBpp0297433


Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATGCGACACACACACTTGT
R:
TGCTGCTGCTATTGTTGGTGT
Band lengths:
308-528
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)