DmeALTA0008178-2/2 @ dm6
Alternative 3'ss
Gene
FBgn0004656 | fs(1)h
Description
The gene female sterile (1) homeotic is referred to in FlyBase by the symbol Dmelfs(1)h (CG2252, FBgn0004656). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (5 unique). Gene sequence location is X:8037808..8061436. Its molecular function is unknown. It is involved in the biological process described with: terminal region determination; dendrite morphogenesis; positive regulation of transcription elongation from RNA polymerase II promoter; negative regulation of transcription, DNA-templated. 69 alleles are reported. The phenotypes of these alleles manifest in: dendrite; metathoracic segment; embryonic/larval cuticle; embryonic/larval spiracle; egg. The phenotypic classes of alleles include: phenotype; increased mortality; some die during P-stage; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
Coordinates
chrX:8051695-8055893:-
Coord C1 exon
chrX:8054123-8055893
Coord A exon
chrX:8053280-8053294
Coord C2 exon
chrX:8051695-8053279
Length
15 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATT
5' ss Score
8.55
3' ss Seq
TGGGTCATTCTGAACCACAGGAT
3' ss Score
4.9
Exon sequences
Seq C1 exon
GCAGCACCAATACGACGACGACAGCGATGGCTGGCGGCGTTGGTGGGCCAGGTGCAGCTGGAGCCAATCCCAATGCTGCCGCCCTGATGGCTAGTCTTCTGAATGCGGGCCAAACGGGCGCCTATCCCGGTGCGCCCGGCCAGACGGCGGTCAATAGCTCCTCGCTTCTAGATGGCAGTACAGCCGCAGTAGCGGCGGCAGCAGCAGCGGCTGCGGCGGCGGCGGCGGCGGCAGGAGGTGCAGCGGGAGCCGCTGGAGGAGCAGGGACAATACCAGCAGTTGCCGTCAATGCCGCTAACGCCGTTCAGGCCTATGTGAATGCGGGCGTGAGCGTCGGAGTGGACGCCGTGATACCGCCTCAGCAGCCCGCCAAAATAAAGAAGGGTGTCAAACGGAAGGCGGACACAACAACGCCGACGGCCAATGCCTTTGAATCCCCGTACACGCAAATGGACTCCAAATCGGCCAAGATTGCGACGCGGCGGGAGTCGAATCGTCAG
Seq A exon
GATCTTACATTCCAG
Seq C2 exon
GGCTCGGGATACAATATGTCGCCGCTAGGCGTCTCCGGAGTGCCCGGACTTGGCGGTCTAGTTGCCGGCGGCGTGGCTGGTGTTGCGGTGGCCAAGAACAAGGAGAAGCTGTCGGATGCGCTCAAGTCGTGCAACGAAATCCTCAAGGAGCTCTTCTCGAAGAAGCACTCGGGCTATGCTTGGCCATTCTACAAGCCAGTGGACGCGGAAATGCTTGGCCTGCATGACTACCACGACATCATCAAGAAACCAATGGATCTGGGCACAGTCAAGCGGAAAATGGACAATCGCGAGTACAAGAGCGCGCCGGAATTTGCCGCCGACGTGCGATTAATATTCACCAACTGCTACAAGTACAATCCGCCAGATCATGATGTTGTGGCCATGGGTCGCAAGCTGCAAGACGTATTTGAGATGCGCTATGCCAACATCCCCGATGAGCCGGTAGCCAATGCGGCCCACCATCACGGACATGGCCACGGGCATGGTCATGGCCATGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0004656-16-10,16-9-2/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.517 A=NA C2=0.530
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=WD(100=19.8)
A:
NA
C2:
PF0043920=Bromodomain=WD(100=16.8)
Main Inclusion Isoform:
FBpp0071074
Main Skipping Isoform:
FBpp0305500
Other Inclusion Isoforms:
FBpp0071073, FBpp0089297, FBpp0089298, FBpp0089299, FBpp0290524, FBpp0305501
Other Skipping Isoforms:
FBpp0305499
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAATGCCTTTGAATCCCCGT
R:
GCGGCGACATATTGTATCCCG
Band lengths:
105-120
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)