Special

DmeALTA0008266-2/2 @ dm6

Alternative 3'ss

Gene
Description
The gene hemipterous is referred to in FlyBase by the symbol Dmelhep (CG4353, FBgn0010303). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (6 unique). Gene sequence location is X:13079205..13090434. Its molecular function is described by 6 unique terms, many of which group under: binding; transferase activity, transferring phosphorus-containing groups; kinase binding; transferase activity; protein binding. It is involved in the biological process described with 36 unique terms, many of which group under: cellular response to chemical stimulus; regulation of lamellipodium assembly; peptidoglycan recognition protein signaling pathway; cellular catabolic process; vascular endothelial growth factor receptor signaling pathway. 48 alleles are reported. The phenotypes of these alleles manifest in: chorionic specialization; adult labral segment; ventral furrow; embryonic/first instar larval cuticle; lamellocyte. The phenotypic classes of alleles include: viable; size defective; stress response defective; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, in adult female stages.
Coordinates
chrX:13080638-13082064:-
Coord C1 exon
chrX:13081513-13082064
Coord A exon
chrX:13081044-13081118
Coord C2 exon
chrX:13080638-13081043
Length
75 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
ACAACGAACCAACCAAACAGGCT
3' ss Score
2.48
Exon sequences
Seq C1 exon
TGAGCGGTATCAGCAGCAGCGCCAGCAGCCGCCCGTTGGAGTGACCAGCACGAATCCGTTTCACAGCAACTATGTGCCGCCGCCGCCATCAACGCACTCCACCTCTAGTCAGTCCTCCACGCAGTCGACGTGTTCGCAAATCGCCATCAATCCCGCCAGCATATCCCCATCGTCTGGTTCCGGAACGGGAAACATGGCGGGATTGGGAATCGGTTCGGCTCCGGCATCGGGATTGGGGGCAGCTGGTCACTTTGGAGCGGGCGGCACTGGCGAGCAGCTGCAGTATCAGCCGCTGCCCATCGCCGCCGAGGCAACGGGAACGAGTCCCACGCTCCAGTCTAGATCACCGGAACAGCAGTCGGATTATGGAGGAAACGGCAACATGGTGGCCAGTAAGCTGAGCAAGCTGTACGCACGCCGACAACTTTTGGGCCAGAGCTCCAGCAGCGGAGCGAGCAATAGCAGCCTGGACGGTTGCAGTCGGGAGCAACACGATGCAG
Seq A exon
GCTGGTTCAACACTCTTGCCGGTGCCATGAAGCGACAGTTTGCCACCTATGTTAAAACCCAATTGAATTCCACAG
Seq C2 exon
CCACGTCGCCGGTGGCGTCCAGCATGGATCGAGACCAGGAGCCAGTGCATCCGCAGCCGCCGGCGTACAGGAGCGTTGTGAATAACGGCAGCGGTGGCAAGTCTTACTACTATCGCACCTTGTCGGCGGCCAGCAGCAGTAGCAATACCAGCCAGAGCACCTCGCCCACGACGGAACCGCTGCCCGGCGGTGGCACCAGTAGCTTTCTGCGTCGCTATGCAAGCAGTGGACCGGGAGGTAGCATCAGCACGCCGCCCAGTCCGCATATCTTGGCGGGATTGGATCGCAGGCATCGAAGTCCAGATCCGCCGCCACGCTACAATCGCGGACAGTCACCGCTATTGCTGCGCAAGAATCTGCTGGAGCTGAGTGGCCAGCCGCCCGGCTCTCCGCTGCTGCACCGAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0010303-14-11,14-10-2/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact

Protein isoform when splice site is used (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.932 A=NA C2=0.924
Domain overlap (PFAM):

C1:
NO
A:
NA
C2:
NO


Main Inclusion Isoform:
FBpp0073578


Main Skipping Isoform:
FBpp0303422


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
FBpp0309264
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGGAGGAAACGGCAACATGG
R:
CTCCTGGTCTCGATCCATGCT
Band lengths:
176-251
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)