Special

FBgn0010303 @ dm6

Biotype
protein_coding
Gene Symbol
hep
Description
The gene hemipterous is referred to in FlyBase by the symbol Dmelhep (CG4353, FBgn0010303). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (6 unique). Gene sequence location is X:13079205..13090434. Its molecular function is described by 6 unique terms, many of which group under: binding; transferase activity, transferring phosphorus-containing groups; kinase binding; transferase activity; protein binding. It is involved in the biological process described with 36 unique terms, many of which group under: cellular response to chemical stimulus; regulation of lamellipodium assembly; peptidoglycan recognition protein signaling pathway; cellular catabolic process; vascular endothelial growth factor receptor signaling pathway. 48 alleles are reported. The phenotypes of these alleles manifest in: chorionic specialization; adult labral segment; ventral furrow; embryonic/first instar larval cuticle; lamellocyte. The phenotypic classes of alleles include: viable; size defective; stress response defective; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, in adult female stages.
Coordinates
chrX:13079205-13090434:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
0
NA
-
66.25
100
0
Alternative 3'ss
75
chrX:13081044-13081118
-
33.75
100
0
Exon Skipping
326
chrX:13084245-13084570
-
52.39
97.17
0
Exon Skipping
22
chrX:13083962-13083983
-
7.61
39.12
0
Exon Skipping
227
chrX:13083342-13083568
-
0.74
14.49
0
Intron Retention
2218
chrX:13087141-13089358
-
4.08
50
0
Intron Retention
73
chrX:13085752-13085824
-
1.99
63.64
0
Intron Retention
2497
chrX:13083099-13085595
-
21.33
44.38
0
Intron Retention
394
chrX:13081119-13081512
-
13.23
86.36
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000076984 MAP2K7 1-to-1
Human hg19 ENSG00000076984 MAP2K7 1-to-1
Mouse mm10 ENSMUSG00000002948 Map2k7 1-to-2
Mouse mm10 ENSMUSG00000109061 Map2k7 1-to-2
Mouse mm9 ENSMUSG00000002948 Map2k7 1-to-2
Rat rn6 ENSRNOG00000001047 Map2k7 1-to-1
Cow bosTau6 ENSBTAG00000010639 MAP2K7 1-to-1
Zebrafish danRer10 ENSDARG00000008279 map2k7 1-to-1