DmeALTD0000192-1/2 @ dm6
Alternative 5'ss
Gene
FBgn0260642 | Antp
Description
The gene Antennapedia is referred to in FlyBase by the symbol DmelAntp (CG1028, FBgn0260642). It is a protein_coding_gene from Dmel. It has 13 annotated transcripts and 13 polypeptides (5 unique). Gene sequence location is 3R:6896253..6999228. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with 13 unique terms, many of which group under: multicellular organism development; multicellular organismal process; developmental process; regionalization; animal organ development. 177 alleles are reported. The phenotypes of these alleles manifest in: circulatory system; melanotic mass; embryonic/larval mesothoracic dorsal sensory cluster; abdomen; neuroblast NB3-3. The phenotypic classes of alleles include: viable; lethal; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis.
Coordinates
chr3R:6896253-6908738:-
Coord C1 exon
chr3R:6908525-6908738
Coord A exon
NA
Coord C2 exon
chr3R:6896253-6898538
Length
0 bp
Sequences
Splice sites
5' ss Seq
TTGGTAAGT
5' ss Score
10.47
3' ss Seq
TATTTACTTGGAACCAACAGAAC
3' ss Score
2.85
Exon sequences
Seq C1 exon
GTCCATCAGAACCATCACAACATGGGCATGTACCAGCAGCAGTCGGGAGTTCCGCCGGTGGGTGCCCCACCTCAGGGCATGATGCACCAGGGCCAGGGTCCTCCACAGATGCACCAGGGACATCCTGGCCAACACACGCCTCCTTCCCAAAACCCGAACTCGCAGTCCTCGGGGATGCCGTCTCCACTGTATCCCTGGATGCGAAGTCAGTTTG
Seq A exon
NA
Seq C2 exon
AACGCAAACGCGGAAGGCAGACATACACCCGGTACCAGACTCTAGAGCTAGAGAAGGAGTTTCACTTCAATCGCTACTTGACCCGTCGGCGAAGGATCGAGATCGCCCACGCCCTGTGCCTCACGGAGCGCCAGATAAAGATTTGGTTCCAGAATCGGCGCATGAAGTGGAAGAAGGAGAACAAGACGAAGGGCGAGCCGGGATCCGGAGGCGAAGGCGACGAGATAACACCACCCAACAGTCCGCAGTAGGATCGACGGAGTCTACCCACTTAAATGAAATTTCTATCTAAATACAATTTACGTTAGTTCGGAGAGCGCAAATGAATTTACTTCGATCCCAGAGGACTATCTAATAACTATCCAATCCGTTGAACTTCGCGTGAACAAACCTAAACTAAACTAAACAAAGAGCAGAGCTGAGAACTCTACCTACAACTTAGTTAATTGTTATTATTTTCTACTTATTATTTAATTGTACACGAAAGGCAAGTGGGGAAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0260642-10-10,11-10-1/2
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.629
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0004624=Homeobox=WD(100=67.9)
Main Inclusion Isoform:
FBpp0089086
Main Skipping Isoform:
FBpp0081161
Other Inclusion Isoforms:
FBpp0089241, FBpp0089242, FBpp0089247
Other Skipping Isoforms:
FBpp0081160, FBpp0081162, FBpp0089243, FBpp0089244, FBpp0089245, FBpp0089246
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTCCTTCCCAAAACCCGAAC
R:
TATGTCTGCCTTCCGCGTTTG
Band lengths:
101-113
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)