DmeALTD0004796-3/3 @ dm6
Alternative 5'ss
Gene
FBgn0085421 | Epac
Description
The gene Exchange protein directly activated by cAMP is referred to in FlyBase by the symbol DmelEpac (CG34392, FBgn0085421). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2R:6759715..6798941. Its molecular function is described by: guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rap protein signal transduction. 20 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period.
Coordinates
chr2R:6796906-6798887:-
Coord C1 exon
chr2R:6798787-6798887
Coord A exon
chr2R:6798625-6798786
Coord C2 exon
chr2R:6796906-6797412
Length
162 bp
Sequences
Splice sites
5' ss Seq
TGCGTGAGT
5' ss Score
7.55
3' ss Seq
CGCCCAATTTAACTTTGCAGCTG
3' ss Score
8.59
Exon sequences
Seq C1 exon
GAGAACTGAAATGTTTGCCCAAGAACTGTATATACCAAGTGCTTGAAAGCCGTTAGCAAGTGGTTCATTTAAATATTCGTTTGAAGTCGGTTCGATTTCAG
Seq A exon
GTATTCGCTGGATTTCGGTATGTCGCGTGGGTTCGAAACTAAAAGTTCATTTTCCGTGCCAAAAAGTGTTTGCCAACAAGAAGGACTTTAAAATATCGAATTCTGCTGCGGGATCTCTGTTACTCTTGCATCTTCTGATCCTTTTCTCCGTTCAGAGGATGC
Seq C2 exon
CTGCTCGGTATCGAAATCCTCGTCGCCAGCCAAACGGGAGCTCAAACTGAAATCCATTTCCAAACTTTCGCCTAATCAACGAGCTACGTCCACTTACCCCTGGCTCCAACTCGAAAGGAGCTCGCTCCAACGCTCCCAAAAGCGGATTTCGAGTGCCTCGCTGGGCCGAGCCACCTGGCATGTCGTATTCAAAGGGAATCGCAGATTGACGGCCACATCGCGGATTGAGGTGACTGCAAACTGGGTGCGAGCGCCGCCATTACTCGGTATTTTGATTTCGCTTTCCTGGGCCGCAACGGGCAATTAATTTGCACCACTTTGGAGCCGCTCCGCCTCGATTTATGTGCTCTGCTCAAAGTTGGGGCAACTATTTGGTTTGGTGTTTGTGGAATGTGCTGTTCATAACTTGTATCATAACTTGTGTCAAACGGCGAAACTAATCGAGCGAGGGAGATTTAAATAAAAATTCAACATGGCGATGGAATGGATAACTGCAATGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0085421-1-0,2-0,3-0-3/3
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.000
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTGAAAGCCGTTAGCAAGTG
R:
TGAATACGACATGCCAGGTGG
Band lengths:
252-414
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)