FBgn0085421 @ dm6
Biotype
protein_coding
Gene Symbol
Epac
Description
The gene Exchange protein directly activated by cAMP is referred to in FlyBase by the symbol DmelEpac (CG34392, FBgn0085421). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2R:6759715..6798941. Its molecular function is described by: guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rap protein signal transduction. 20 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period.
Coordinates
chr2R:6759715-6798941:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000079337 | RAPGEF3 | 1-to-4 |
| Human | hg38 | ENSG00000091428 | RAPGEF4 | 1-to-4 |
| Human | hg38 | ENSG00000108352 | RAPGEFL1 | 1-to-4 |
| Human | hg38 | ENSG00000136237 | RAPGEF5 | 1-to-4 |
| Human | hg19 | ENSG00000079337 | RAPGEF3 | 1-to-4 |
| Human | hg19 | ENSG00000091428 | RAPGEF4 | 1-to-4 |
| Human | hg19 | ENSG00000108352 | RAPGEFL1 | 1-to-4 |
| Human | hg19 | ENSG00000136237 | RAPGEF5 | 1-to-4 |
| Mouse | mm10 | ENSMUSG00000022469 | Rapgef3 | 1-to-4 |
| Mouse | mm10 | ENSMUSG00000038020 | Rapgefl1 | 1-to-4 |
| Mouse | mm10 | ENSMUSG00000041992 | Rapgef5 | 1-to-4 |
| Mouse | mm10 | ENSMUSG00000049044 | Rapgef4 | 1-to-4 |
| Mouse | mm9 | ENSMUSG00000022469 | Rapgef3 | 1-to-4 |
| Mouse | mm9 | ENSMUSG00000038020 | Rapgefl1 | 1-to-4 |
| Mouse | mm9 | ENSMUSG00000041992 | Rapgef5 | 1-to-4 |
| Mouse | mm9 | ENSMUSG00000049044 | Rapgef4 | 1-to-4 |
| Rat | rn6 | ENSRNOG00000001516 | Rapgef4 | 1-to-4 |
| Rat | rn6 | ENSRNOG00000005271 | Rapgef5 | 1-to-4 |
| Rat | rn6 | ENSRNOG00000027871 | AC141969.1 | 1-to-4 |
| Rat | rn6 | ENSRNOG00000059961 | Rapgef3 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000006828 | RAPGEF3 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000015232 | RAPGEFL1 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000015539 | RAPGEF5 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000020984 | RAPGEF4 | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000074307 | rapgef5b | 1-to-6 |
| Zebrafish | danRer10 | ENSDARG00000075271 | rapgef5a | 1-to-6 |
| Zebrafish | danRer10 | ENSDARG00000079291 | rapgef3 | 1-to-6 |
| Zebrafish | danRer10 | ENSDARG00000079872 | rapgef4 | 1-to-6 |
| Zebrafish | danRer10 | ENSDARG00000079912 | rapgefl1 | 1-to-6 |