DmeALTD0005538-2/4 @ dm6
Alternative 5'ss
Gene
FBgn0264695 | Mhc
Description
The gene Myosin heavy chain is referred to in FlyBase by the symbol DmelMhc (CG17927, FBgn0264695). It is a protein_coding_gene from Dmel. It has 22 annotated transcripts and 22 polypeptides (20 unique). Gene sequence location is 2L:16766566..16788766. Its molecular function is described by 6 unique terms, many of which group under: nucleoside-triphosphatase activity; catalytic activity; hydrolase activity, acting on acid anhydrides; drug binding; actin filament binding. It is involved in the biological process described with 15 unique terms, many of which group under: epithelial cell development; adult somatic muscle development; regulation of biological quality; reproductive process; protein stabilization. 161 alleles are reported. The phenotypes of these alleles manifest in: somatic cell of ovariole; muscle attachment site; embryonic/larval heart; adult visceral muscle; germline cell. The phenotypic classes of alleles include: sterile; fertile; phenotype; increased mortality during development.
Coordinates
chr2L:16767777-16768884:+
Coord C1 exon
chr2L:16767777-16767941
Coord A exon
chr2L:16767942-16767954
Coord C2 exon
chr2L:16768584-16768884
Length
13 bp
Sequences
Splice sites
5' ss Seq
CCAGTTGAG
5' ss Score
-17.25
3' ss Seq
TTTCTTTTGTATATTTACAGGGA
3' ss Score
9.26
Exon sequences
Seq C1 exon
AATTCGAATCGAATTTTCGATTGTCGATTTAGTGTGGATTGTCGAAAATCGTTCCGCCTTCGAAGTTTACTGAAAGGAATCATTGCGATCTCGTGAATTGCTTGTATGAGAACACGCCACCATATCGAGATACCTGTTCAAAATATCGAAATCGCGTTCCAAACG
Seq A exon
GTAGTAGTTACCA
Seq C2 exon
GGAAGTTTTGGGCTCACGACGCGATTAACAAAGAAATTTTGAAAAGTCCCAATATTATTTTTCGAGTTTTTAAGTTTCTAAACGAAATTTAAGCAAGATGCCGAAGCCAGTCGCAAATCAGGAGGATGAGGATCCCACCCCATACCTGTTCGTGTCTTTGGAGCAAAGGCGTATCGATCAATCGAAACCCTATGACTCGAAGAAGTCTTGCTGGATCCCCGACGAGAAGGAGGGTTATCTCCTTGGTGAGATCAAGGCCACCAAGGGCGATATCGTCTCCGTTGGTCTGCAGGGTGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0264695-4-2,5-2,6-2,7-2-2/4
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.225
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
PF0273614=Myosin_N=PU(78.6=48.5)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTTGTATGAGAACACGCCA
R:
TTGTTAATCGCGTCGTGAGCC
Band lengths:
98-111
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)