Special

FBgn0264695 @ dm6

Biotype
protein_coding
Gene Symbol
Mhc
Description
The gene Myosin heavy chain is referred to in FlyBase by the symbol DmelMhc (CG17927, FBgn0264695). It is a protein_coding_gene from Dmel. It has 22 annotated transcripts and 22 polypeptides (20 unique). Gene sequence location is 2L:16766566..16788766. Its molecular function is described by 6 unique terms, many of which group under: nucleoside-triphosphatase activity; catalytic activity; hydrolase activity, acting on acid anhydrides; drug binding; actin filament binding. It is involved in the biological process described with 15 unique terms, many of which group under: epithelial cell development; adult somatic muscle development; regulation of biological quality; reproductive process; protein stabilization. 161 alleles are reported. The phenotypes of these alleles manifest in: somatic cell of ovariole; muscle attachment site; embryonic/larval heart; adult visceral muscle; germline cell. The phenotypic classes of alleles include: sterile; fertile; phenotype; increased mortality during development.
Coordinates
chr2L:16766566-16788766:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
0
NA
+
48.76
49.3
0
Alternative 3'ss
66
chr2L:16786551-16786616
+
27.82
25.03
0
Alternative 3'ss
0
NA
+
24.49
59.94
0
Alternative 3'ss
438
chr2L:16787079-16787516
+
75.48
59.94
0
Alternative 5'ss
0
NA
+
10.65
50
0
Alternative 5'ss
13
chr2L:16767942-16767954
+
13.81
18.98
0
Alternative 5'ss
18
chr2L:16767942-16767959
+
73.97
45.85
0
Exon Skipping
144
chr2L:16769459-16769602
+
79.58
97.4
1
Exon Skipping
104
chr2L:16771343-16771446
+
56.27
100
3
Exon Skipping
104
chr2L:16773277-16773380
+
31.24
99.85
3
Exon Skipping
118
chr2L:16777631-16777748
+
11.78
99.08
3
Exon Skipping
118
chr2L:16778005-16778122
+
4.39
63.74
2
Exon Skipping
118
chr2L:16778390-16778507
+
20.46
94.88
2
Exon Skipping
118
chr2L:16779093-16779210
+
46.4
98.99
4
Exon Skipping
118
chr2L:16779728-16779845
+
11.67
83.22
2
Exon Skipping
79
chr2L:16783833-16783911
+
15.4
98.97
2
Exon Skipping
79
chr2L:16784251-16784329
+
83.67
99.29
2
Exon Skipping
502
chr2L:16787079-16787580
+
17.17
99.06
0
Exon Skipping
104
chr2L:16771942-16772045
+
10.02
96.77
0
Intron Retention
2288
chr2L:16777440-16779727
+
11.1
59.65
0
Intron Retention
704
chr2L:16779846-16780549
+
6.49
71.43
0
Intron Retention
589
chr2L:16783662-16784250
+
3.29
86.96
0
Intron Retention
201
chr2L:16771142-16771342
+
8.13
100
0
Intron Retention
825
chr2L:16774858-16775682
+
3.66
74.36
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000006788 MYH13 1-to-10
Human hg38 ENSG00000109061 MYH1 1-to-10
Human hg38 ENSG00000125414 MYH2 1-to-10
Human hg38 ENSG00000133020 MYH8 1-to-10
Human hg38 ENSG00000264424 MYH4 1-to-10
Human hg19 ENSG00000006788 MYH13 1-to-10
Human hg19 ENSG00000109061 MYH1 1-to-10
Human hg19 ENSG00000125414 MYH2 1-to-10
Human hg19 ENSG00000133020 MYH8 1-to-10
Mouse mm10 ENSMUSG00000020908 Myh3 1-to-7
Mouse mm10 ENSMUSG00000053093 Myh7 1-to-7
Mouse mm10 ENSMUSG00000055775 Myh8 1-to-7
Mouse mm10 ENSMUSG00000060180 Myh13 1-to-7
Mouse mm10 ENSMUSG00000074652 Myh7b 1-to-7
Mouse mm9 ENSMUSG00000020908 Myh3 1-to-7
Mouse mm9 ENSMUSG00000053093 Myh7 1-to-7
Mouse mm9 ENSMUSG00000055775 Myh8 1-to-7
Mouse mm9 ENSMUSG00000060180 Myh13 1-to-7
Mouse mm9 ENSMUSG00000074652 Myh7b 1-to-7
Rat rn6 ENSRNOG00000016983 Myh7 1-to-6
Rat rn6 ENSRNOG00000018997 Myh7b 1-to-6
Rat rn6 ENSRNOG00000025757 Myh6 1-to-6
Rat rn6 ENSRNOG00000049695 Myh1 1-to-6
Rat rn6 ENSRNOG00000061038 Myh15 1-to-6
Cow bosTau6 ENSBTAG00000003512 MYH7B 1-to-8
Cow bosTau6 ENSBTAG00000009702 MYHC-FETAL 1-to-8
Cow bosTau6 ENSBTAG00000018204 MYH1 1-to-8
Cow bosTau6 ENSBTAG00000025337 MYH13 1-to-8
Cow bosTau6 ENSBTAG00000037794 MYH4 1-to-8
Chicken galGal4 ENSGALG00000027323 1-to-12
Zebrafish danRer10 ENSDARG00000067995 myhz1.2 1-to-12
Zebrafish danRer10 ENSDARG00000095217 zgc:66156 1-to-12
Zebrafish danRer10 ENSDARG00000098747 CU633479.1 1-to-12
Zebrafish danRer10 ENSDARG00000099959 smyhc1 1-to-12
Zebrafish danRer10 ENSDARG00000102414 wu:fd14a01 1-to-12