DmeALTD0005720-1/2 @ dm6
Alternative 5'ss
Gene
FBgn0015773 | NetA
Description
The gene Netrin-A is referred to in FlyBase by the symbol DmelNetA (CG18657, FBgn0015773). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:14604012..14653928. Its molecular function is unknown. It is involved in the biological process described with 9 unique terms, many of which group under: animal organ development; cell motility; sensory organ development; tissue development; regulation of cell development. 27 alleles are reported. The phenotypes of these alleles manifest in: axon; photoreceptor cell R8 stalk; cellular anatomical entity; commissure; cell projection. The phenotypic classes of alleles include: neuroanatomy defective; oxidative stress response defective; viable; size defective; cell migration defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis.
Coordinates
chrX:14606483-14610591:-
Coord C1 exon
chrX:14610439-14610591
Coord A exon
NA
Coord C2 exon
chrX:14606483-14606548
Length
0 bp
Sequences
Splice sites
5' ss Seq
GGGGTAAGT
5' ss Score
9.65
3' ss Seq
CCATTTTATCGCCTTTTCAGAAT
3' ss Score
9.66
Exon sequences
Seq C1 exon
AACAACCACCGCGTATGATCAACATGCTGGACACCCAGAATACCGCTCCCGAGCCGGATGAGCCCGAATCCTCTCCAGGATCTGGTGGCGACCGCAACGGCGCCGCCGGAATGGCCGCCCAGTCTCAGTACTATCGCACCGAGGGCGGCAGGG
Seq A exon
NA
Seq C2 exon
AATGCGGCAAATGCAGAGTCAGCACCAAAAGGCTAAACCTAAACAAGTTCTGCAAAAGAGACTACG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0015773-6-5,7-5-1/2
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.796 A=NA C2=0.333
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
FBpp0073759
Main Skipping Isoform:
FBpp0300656
Other Inclusion Isoforms:
FBpp0311922
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGGATCTGGTGGCGACC
R:
TGACTCTGCATTTGCCGCATT
Band lengths:
100-104
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)