Special

DmeALTD0007620-1/2 @ dm6

Alternative 5'ss

Gene
Description
The gene crinkled is referred to in FlyBase by the symbol Dmelck (CG7595, FBgn0000317). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2L:15044963..15057862. Its molecular function is described by 6 unique terms, many of which group under: protein binding; hydrolase activity; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; cytoskeletal protein binding; pyrophosphatase activity. It is involved in the biological process described with 12 unique terms, many of which group under: actin filament-based movement; chaeta development; organelle organization; cuticle development involved in chitin-based cuticle molting cycle; hair cell differentiation. 49 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; male-specific anatomical entity; cell projection; portion of tissue; germline cell. The phenotypic classes of alleles include: lethal; phenotype; lethal - all die before end of P-stage; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during early larval stages.
Coordinates
chr2L:15053414-15057768:-
Coord C1 exon
chr2L:15057668-15057768
Coord A exon
NA
Coord C2 exon
chr2L:15053414-15053522
Length
0 bp
Sequences
Splice sites
5' ss Seq
CTGGTGCGT
5' ss Score
8.29
3' ss Seq
CTTGTTCTCTCTTTCGGCAGAGA
3' ss Score
9.33
Exon sequences
Seq C1 exon
CAGCCCCAAAATGATCAGTGGTCTGTAATCCACCTGTTGCTCGGCTTAACTGTGCTGGAAAAGCGGACTTTCGGCGCGCTGCTCTATTCCTGCGACTGCTG
Seq A exon
NA
Seq C2 exon
AGAAGAATATAACCCAAGCGGCAGCAGCGAAAAGGAACGGGCCATTGTCCCTGGATGCCAACACAGGATCAGTAAATGAAGGACGACGAACATGGTGATCGTAACACGT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0000317-0-1,1-1-1/2
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact

5' UTR

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=NA C2=0.000
Domain overlap (PFAM):

C1:
NA
A:
NA
C2:
NO


Main Inclusion Isoform:
NA


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCCCCAAAATGATCAGTGGT
R:
ACGTGTTACGATCACCATGTTCG
Band lengths:
210-373
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)