Special

DmeALTD0008004-4/7 @ dm6

Alternative 5'ss

Gene
FBgn0004656 | fs(1)h
Description
The gene female sterile (1) homeotic is referred to in FlyBase by the symbol Dmelfs(1)h (CG2252, FBgn0004656). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (5 unique). Gene sequence location is X:8037808..8061436. Its molecular function is unknown. It is involved in the biological process described with: terminal region determination; dendrite morphogenesis; positive regulation of transcription elongation from RNA polymerase II promoter; negative regulation of transcription, DNA-templated. 69 alleles are reported. The phenotypes of these alleles manifest in: dendrite; metathoracic segment; embryonic/larval cuticle; embryonic/larval spiracle; egg. The phenotypic classes of alleles include: phenotype; increased mortality; some die during P-stage; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
Coordinates
chrX:8059867-8060974:-
Coord C1 exon
chrX:8060917-8060974
Coord A exon
chrX:8060877-8060916
Coord C2 exon
chrX:8059867-8060158
Length
40 bp
Sequences
Splice sites
5' ss Seq
GTGGTAAAA
5' ss Score
2.98
3' ss Seq
TTTTGTTTTTATTTTTACAGTTG
3' ss Score
9.73
Exon sequences
Seq C1 exon
TTGTATATTTGATGGCGACTCAGAAGAAACTCGCGCGTTTGTCGAAAAATCGTAGCGC
Seq A exon
GTACGTATATATCGGTGTGTAGAAATTACTAAAAATTGTG
Seq C2 exon
TTGCAACTTTTTAACAATCGTGTACAATCTGTATGTTGTATATGTTCAATTCAAAATTCAGCAACAATAGCAACAACGCAATTCAGCAACAACAACAAACAAAACCGACAAGCTAAACTTGGCTAAGACAAAATCAACATCCAGCGGCAGCGCGGCCATAAACAAAGCCAAAATCAAAAGTCATTCGGATATATACATATATTCGCCCATAATAGCGAATAAACAGTAACAGAACGAGTGGATTTAACGAAACAACAAAAAGAAAAGAAGAACGATAAAATCCAAAGGAAAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0004656-3-1,4-1,5-1,6-1,7-1,8-1,9-1-4/7
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact

5' UTR

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=NA C2=NA
Domain overlap (PFAM):

C1:
NA
A:
NA
C2:
NA


Main Inclusion Isoform:
NA


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCGACTCAGAAGAAACTCGC
R:
TTGCTGAATTGCGTTGTTGCT
Band lengths:
134-174
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)