DmeALTD0008467-1/3 @ dm6
Alternative 5'ss
Gene
FBgn0035247 | metl
Description
The gene methyltransferase-like is referred to in FlyBase by the symbol Dmelmetl (CG13929, FBgn0035247). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:1637942..1639235. Its molecular function is described by: tRNA (cytosine) methyltransferase activity; tRNA (cytosine-3-)-methyltransferase activity. It is involved in the biological process described with: tRNA methylation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; wild-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.
Coordinates
chr3L:1637942-1639142:-
Coord C1 exon
chr3L:1639042-1639142
Coord A exon
NA
Coord C2 exon
chr3L:1637942-1638854
Length
0 bp
Sequences
Splice sites
5' ss Seq
TTGGTAAAT
5' ss Score
4.94
3' ss Seq
CTCTAAACATGGATTCACAGGGA
3' ss Score
3.38
Exon sequences
Seq C1 exon
TCCGATATGAGTGACAACCCCGCCGCGGAGAACGAAAAGCGACCGCAGTTCGGAACCCGCCTGCTCACGGATGCTGACGACGTCTTCAAGCACAATGCTTG
Seq A exon
NA
Seq C2 exon
GGACCACGTGCAATGGGATGAAGAGCAGGAACTGGCCGCGAAGGCGGCTGTAGCCAAGAATTCGACCTCAAAGATGGAAGCGGAGCAGAAGGAGCGATTTCAGACAGACGCCCCCAAGTTTTGGGATTCCTTCTACGGCATTCACGACAACCGCTTCTTCAAGGATCGCCACTGGCTGTTTACGGAGTTCCCCGAACTAGCTCCTCTGGCGGCGGATTCGGCGGTACTGCAACCACGTAGCATTTTCGAACTGGGCTGTGGAGTAGGAAACACAATTTTACCCCTTCTACAGTACAGCTCTGAACCGCAGCTCAAGGTTTTCGGATGTGACTTCTCCGCCCGGGCCATTGAAATCCTGCGAAGCCAACGGCAGTTCGACGAGAAGCGCTGCGAGGTGTTTGTCATGGATGCCACGCTGGATCATTGGCAGGTGCCCTTCGAGGAAAACTCACAGGACATTATTGTGATGATTTTTGTGCTGTCCGCAATTGAGCCAAAGA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0035247-0-0,1-0,2-0-1/3
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.310 A=NA C2=0.037
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF082427=Methyltransf_12=WD(100=38.2)
Main Inclusion Isoform:
FBpp0072695
Main Skipping Isoform:
FBpp0072696
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGATATGAGTGACAACCCCGC
R:
GGTTGTCGTGAATGCCGTAGA
Band lengths:
251-364
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)