Special

FBgn0035247 @ dm6

Biotype
protein_coding
Gene Symbol
metl
Description
The gene methyltransferase-like is referred to in FlyBase by the symbol Dmelmetl (CG13929, FBgn0035247). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:1637942..1639235. Its molecular function is described by: tRNA (cytosine) methyltransferase activity; tRNA (cytosine-3-)-methyltransferase activity. It is involved in the biological process described with: tRNA methylation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; wild-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.
Coordinates
chr3L:1637942-1639235:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 5'ss
0
NA
-
65.61
70.53
0
Alternative 5'ss
133
chr3L:1638909-1639041
-
34.31
70.53
0
Intron Retention
187
chr3L:1638855-1639041
-
25.65
52.2
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000087995 METTL2A 1-to-3
Human hg38 ENSG00000123600 METTL8 1-to-3
Human hg38 ENSG00000165055 METTL2B 1-to-3
Human hg19 ENSG00000087995 METTL2A 1-to-3
Human hg19 ENSG00000123600 METTL8 1-to-3
Human hg19 ENSG00000165055 METTL2B 1-to-3
Mouse mm10 ENSMUSG00000020691 Mettl2 1-to-2
Mouse mm10 ENSMUSG00000041975 Mettl8 1-to-2
Mouse mm9 ENSMUSG00000020691 Mettl2 1-to-2
Mouse mm9 ENSMUSG00000041975 Mettl8 1-to-2
Rat rn6 ENSRNOG00000006131 Mettl2b 1-to-2
Rat rn6 ENSRNOG00000009382 AABR07052486.1 1-to-2
Cow bosTau6 ENSBTAG00000009458 METTL2 1-to-2
Cow bosTau6 ENSBTAG00000016430 METTL8 1-to-2
Chicken galGal4 ENSGALG00000000396 METTL2A 1-to-2
Chicken galGal4 ENSGALG00000009564 METTL8 1-to-2
Chicken galGal3 ENSGALG00000000396 METTL2A 1-to-2
Chicken galGal3 ENSGALG00000009564 METTL8 1-to-2
Zebrafish danRer10 ENSDARG00000008105 mettl2a 1-to-2
Zebrafish danRer10 ENSDARG00000017359 mettl8 1-to-2