DmeEX0000101 @ dm6

FBgn0000017 | Abl

The gene Abl tyrosine kinase is referred to in FlyBase by the symbol DmelAbl (CG4032, FBgn0000017). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (9 unique). Gene sequence location is 3L:16615866..16647882. Its molecular function is described by: protein tyrosine kinase activity; protein binding; non-membrane spanning protein tyrosine kinase activity; ATP binding. It is involved in the biological process described with 28 unique terms, many of which group under: protein localization; cell migration; lamellipodium organization; regulation of protein stability; chemical synaptic transmission. 59 alleles are reported. The phenotypes of these alleles manifest in: multidendritic neuron; cellular anatomical entity; embryonic/larval cuticle; actin cytoskeleton; amnioserosa. The phenotypic classes of alleles include: increased mortality during development; some die during embryonic stage; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.