FBgn0000017 @ dm6
Biotype
protein_coding
Gene Symbol
Abl
Description
The gene Abl tyrosine kinase is referred to in FlyBase by the symbol DmelAbl (CG4032, FBgn0000017). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (9 unique). Gene sequence location is 3L:16615866..16647882. Its molecular function is described by: protein tyrosine kinase activity; protein binding; non-membrane spanning protein tyrosine kinase activity; ATP binding. It is involved in the biological process described with 28 unique terms, many of which group under: protein localization; cell migration; lamellipodium organization; regulation of protein stability; chemical synaptic transmission. 59 alleles are reported. The phenotypes of these alleles manifest in: multidendritic neuron; cellular anatomical entity; embryonic/larval cuticle; actin cytoskeleton; amnioserosa. The phenotypic classes of alleles include: increased mortality during development; some die during embryonic stage; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.
Coordinates
chr3L:16615866-16647882:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000097007 | ABL1 | 1-to-2 |
Human | hg38 | ENSG00000143322 | ABL2 | 1-to-2 |
Human | hg19 | ENSG00000097007 | ABL1 | 1-to-2 |
Human | hg19 | ENSG00000143322 | ABL2 | 1-to-2 |
Mouse | mm10 | ENSMUSG00000026596 | Abl2 | 1-to-2 |
Mouse | mm10 | ENSMUSG00000026842 | Abl1 | 1-to-2 |
Mouse | mm9 | ENSMUSG00000026596 | Abl2 | 1-to-2 |
Mouse | mm9 | ENSMUSG00000026842 | Abl1 | 1-to-2 |
Rat | rn6 | ENSRNOG00000004305 | Abl2 | 1-to-3 |
Rat | rn6 | ENSRNOG00000009371 | LOC100909750 | 1-to-3 |
Rat | rn6 | ENSRNOG00000047356 | Abl1 | 1-to-3 |
Cow | bosTau6 | ENSBTAG00000015026 | ABL2 | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000017976 | ABL1 | 1-to-2 |
Chicken | galGal4 | ENSGALG00000003875 | ABL | 1-to-3 |
Chicken | galGal3 | ENSGALG00000003875 | ABL1 | 1-to-3 |
Zebrafish | danRer10 | ENSDARG00000013841 | abl2 | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000035187 | abl1 | 1-to-2 |