Special

FBgn0000017 @ dm6

Biotype
protein_coding
Gene Symbol
Abl
Description
The gene Abl tyrosine kinase is referred to in FlyBase by the symbol DmelAbl (CG4032, FBgn0000017). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (9 unique). Gene sequence location is 3L:16615866..16647882. Its molecular function is described by: protein tyrosine kinase activity; protein binding; non-membrane spanning protein tyrosine kinase activity; ATP binding. It is involved in the biological process described with 28 unique terms, many of which group under: protein localization; cell migration; lamellipodium organization; regulation of protein stability; chemical synaptic transmission. 59 alleles are reported. The phenotypes of these alleles manifest in: multidendritic neuron; cellular anatomical entity; embryonic/larval cuticle; actin cytoskeleton; amnioserosa. The phenotypic classes of alleles include: increased mortality during development; some die during embryonic stage; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.
Coordinates
chr3L:16615866-16647882:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 5'ss
0
NA
-
79.19
94.56
0
Alternative 5'ss
255
chr3L:16626273-16626527
-
20.81
94.56
0
Exon Skipping
54
chr3L:16631377-16631430
-
60.17
97.47
0
Intron Retention
309
chr3L:16627193-16627501
-
18.76
54.37
0
Intron Retention
126
chr3L:16626617-16626742
-
11.74
89.47
0
Intron Retention
1253
chr3L:16625275-16626527
-
11.12
21.74
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000097007 ABL1 1-to-2
Human hg38 ENSG00000143322 ABL2 1-to-2
Human hg19 ENSG00000097007 ABL1 1-to-2
Human hg19 ENSG00000143322 ABL2 1-to-2
Mouse mm10 ENSMUSG00000026596 Abl2 1-to-2
Mouse mm10 ENSMUSG00000026842 Abl1 1-to-2
Mouse mm9 ENSMUSG00000026596 Abl2 1-to-2
Mouse mm9 ENSMUSG00000026842 Abl1 1-to-2
Rat rn6 ENSRNOG00000004305 Abl2 1-to-3
Rat rn6 ENSRNOG00000009371 LOC100909750 1-to-3
Rat rn6 ENSRNOG00000047356 Abl1 1-to-3
Cow bosTau6 ENSBTAG00000015026 ABL2 1-to-2
Cow bosTau6 ENSBTAG00000017976 ABL1 1-to-2
Chicken galGal4 ENSGALG00000003875 ABL 1-to-3
Chicken galGal3 ENSGALG00000003875 ABL1 1-to-3
Zebrafish danRer10 ENSDARG00000013841 abl2 1-to-2
Zebrafish danRer10 ENSDARG00000035187 abl1 1-to-2