DmeEX0000125 @ dm6
Exon Skipping
Gene
FBgn0263120 | Acsl
Description
The gene Acyl-CoA synthetase long-chain is referred to in FlyBase by the symbol DmelAcsl (CG8732, FBgn0263120). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (4 unique). Gene sequence location is 2R:8665813..8683022. Its molecular function is described by: long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. It is involved in the biological process described with 11 unique terms, many of which group under: developmental process; multicellular organism development; cell development; cell communication; lipid storage. 52 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; adult segment; embryonic abdominal segment 6; epithelial cell; cell. The phenotypic classes of alleles include: lethal; lethal - all die before end of larval stage; increased mortality; phenotype.
Coordinates
chr2R:8666171-8674871:+
Coord C1 exon
chr2R:8666171-8666311
Coord A exon
chr2R:8666768-8666794
Coord C2 exon
chr2R:8674647-8674871
Length
27 bp
Sequences
Splice sites
3' ss Seq
CTCACACAACTGCTGCTCAGAGC
3' ss Score
1.93
5' ss Seq
AAGGTAAGT
5' ss Score
11
Exon sequences
Seq C1 exon
TCAGAAACAAACTTAACGTGATTTGAGAACGTTGTGCGCCATTCCGTCACTTCTGCGGGCGCCAAACTAACTTAAGCAAAAAGTTACTAAAAACAACATTGAAACGCAGTTTATGAAATACAACTCACTATCGTATTGTGT
Seq A exon
AGCTGCGAACTAGCCTCTATAAGAAAG
Seq C2 exon
GTGAAACTACAAACTGAACATCTGGAGAGGAACAACTGACATCATCCTATTGTATTATTGTTGCGTCCATTGTTCGTTTGTTCTTGCCATTAATCAGAGCTGGGCTCTTTTGGAGGATACGCCTCACACCCACCATTTTCACTACCGATCAAAAAACACTCATTTAATTCATAGATCGGACAAGTAGAGAAAAGGCAGCAAGATGTTCATCGAAGACGATGCGCA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263120_MULTIEX1-1/4=C1-2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0099845
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGGGCGCCAAACTAACTTAA
R:
TGTCAGTTGTTCCTCTCCAGA
Band lengths:
128-155
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)