DmeEX0000126 @ dm6
Exon Skipping
Gene
FBgn0263120 | Acsl
Description
The gene Acyl-CoA synthetase long-chain is referred to in FlyBase by the symbol DmelAcsl (CG8732, FBgn0263120). It is a protein_coding_gene from Dmel. It has 11 annotated transcripts and 11 polypeptides (4 unique). Gene sequence location is 2R:8665813..8683022. Its molecular function is described by: long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. It is involved in the biological process described with 11 unique terms, many of which group under: developmental process; multicellular organism development; cell development; cell communication; lipid storage. 52 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; adult segment; embryonic abdominal segment 6; epithelial cell; cell. The phenotypic classes of alleles include: lethal; lethal - all die before end of larval stage; increased mortality; phenotype.
Coordinates
chr2R:8666171-8676607:+
Coord C1 exon
chr2R:8666171-8666311
Coord A exon
chr2R:8674647-8674871
Coord C2 exon
chr2R:8676472-8676607
Length
225 bp
Sequences
Splice sites
3' ss Seq
TGTTCTTTTATCGGTTGCAGGTG
3' ss Score
10.28
5' ss Seq
GCAGTAAGT
5' ss Score
9.07
Exon sequences
Seq C1 exon
TCAGAAACAAACTTAACGTGATTTGAGAACGTTGTGCGCCATTCCGTCACTTCTGCGGGCGCCAAACTAACTTAAGCAAAAAGTTACTAAAAACAACATTGAAACGCAGTTTATGAAATACAACTCACTATCGTATTGTGT
Seq A exon
GTGAAACTACAAACTGAACATCTGGAGAGGAACAACTGACATCATCCTATTGTATTATTGTTGCGTCCATTGTTCGTTTGTTCTTGCCATTAATCAGAGCTGGGCTCTTTTGGAGGATACGCCTCACACCCACCATTTTCACTACCGATCAAAAAACACTCATTTAATTCATAGATCGGACAAGTAGAGAAAAGGCAGCAAGATGTTCATCGAAGACGATGCGCA
Seq C2 exon
AATGGACAGCTTCTGGGTGCAGAGCGCTATTGGCGCGATCAAGGCGATCGCCTTTGTCTACGACATCATCACCCTTCCGGTTTACTTGGTGCTGCAGAAGCCCTGGAAACGCCGTCAGGACTCGCGTCGCGTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263120_MULTIEX1-2/4=C1-3
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. ATG (>10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.004
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0087779
Main Skipping Isoform:
FBpp0099845
Other Inclusion Isoforms:
FBpp0087780, FBpp0099846, FBpp0099849
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACAAACTTAACGTGATTTGAGAACG
R:
CGAGTCCTGACGGCGTTTC
Band lengths:
260-485
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)