Special

DmeEX0001770 @ dm6

Exon Skipping

Gene
FBgn0052373 | CG32373
Description
This gene is referred to in FlyBase by the symbol DmelCG32373 (FBgn0052373). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:7650548..7759123. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: synaptic target recognition. 39 alleles are reported. The phenotypes of these alleles manifest in: eye; ommatidium. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr3L:7737113-7757587:+
Coord C1 exon
chr3L:7737113-7737199
Coord A exon
chr3L:7756983-7757179
Coord C2 exon
chr3L:7757292-7757587
Length
197 bp
Sequences
Splice sites
3' ss Seq
AATTAAGTGTGTACTTTTAGGCA
3' ss Score
4.47
5' ss Seq
CAGGTATGT
5' ss Score
9.8
Exon sequences
Seq C1 exon
CTGCCGTTTCCATTGGCTTCTCCTCGCCAGCCGCCAAATCGACTCGACAATTTATCAAAATATTTACATAGACGAGAGAGACCCAAG
Seq A exon
GCAGACATTTTAATGCAAGTTGGTGACAAGCGCCTCAATGGGAGACACTTGATTAAACAAAACGTTTACTTTCGGCTGATGTTTTCTTAAGTAATCCAATCATGAACATGTTTATATAATTATTGAAATGGTGCAAAACAGAATGTCGACATCAGTGATTGTTTTGTACGCGCTTATGTGTATCGCATTTTCCACAG
Seq C2 exon
CTTCGTTAAATGATATTCCCGAAATCACCCCCGCAATAGATAACAATTTATCTTTTCAATACGACGATACCTGCTGGACTCCTCCGAGGATTAAAAATGCTAAGGCATCCGTCAAACTTCGCCGAAATGGGGAACATGTCTTTCTTGTGACCTATTATTCCTGCCGCGTCAACTACAAACTCAAACGTGCCAAAGATAATGCACTCTATTGCTCAAATGGTATATGGCTTGGTTTGAAACCCAATTGCATAAAGATTGGTAAAGGAAACACGCATTCAATGAAGCAAAAAAAAATG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0052373-'3-7,'3-6,7-7
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref, Alt. ATG (>10 exons))

No structure available
Features
Disorder rate (Iupred):
  C1=NA A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
NA
A:
NO
C2:
PF0008415=Sushi=WD(100=59.6)


Main Inclusion Isoform:
FBpp0076517


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0076518, FBpp0306184


Other Skipping Isoforms:
NA
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTCCATTGGCTTCTCCTCGC
R:
GTAGTTGACGCGGCAGGAATA
Band lengths:
257-454
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)