DmeEX0002425 @ dm6
Exon Skipping
Gene
FBgn0261554 | CG42672
Description
This gene is referred to in FlyBase by the symbol DmelCG42672 (FBgn0261554). It is a protein_coding_gene from Dmel. It has 17 annotated transcripts and 17 polypeptides (16 unique). Gene sequence location is 2R:21295652..21310411. Its molecular function is described by: . It is involved in the biological process described with: . 13 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: fertile; partially lethal - majority die; some die during pupal stage; viable; visible. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early pupal stages, in stages of adults of both sexes.
Coordinates
chr2R:21295652-21304019:+
Coord C1 exon
chr2R:21295652-21296213
Coord A exon
chr2R:21299837-21300371
Coord C2 exon
chr2R:21303885-21304019
Length
535 bp
Sequences
Splice sites
3' ss Seq
CTAACTAAGCCACGTCCTAGATA
3' ss Score
-2.6
5' ss Seq
CACGTAAAT
5' ss Score
-0.12
Exon sequences
Seq C1 exon
GTTGCTCGCGGAATAAAATAAGCAAATAATAGTTAAATGGCAATAGTGGGTCACCAACTAGCCGCCAGTTTTTTCTAACTGATTGTGTAATGTTCTAAAAGTGAAGTGCGTACAAAAAAGAGAACGCGTACAGTGCCGTTGATTGCTTAAACAAAAAGTCATCAATTTGTTTTTGTGTGGCTTTGTTGTTTGTGAATGCCCAGGAAATATTTAATTCACACGACAGTTACTCAAGTGCCGCACGTTCTTTGTGCGATTAAGAAAAATATTTTATCGACGTTTCAGTTGGCACCCACACACTGAGCCACCCGCACTCACACAGATACGGCTACGCGGATACAGATACATATACAGATACACGTGCGCTCAGCTGTTGTCGAGAGCTGCTCAGCTGTAGTTTGTTGTCATTCCGTCTCGAGATCCAGATCCCAGAAAATCCCAAGGATATACCCCCAAAAATCCGGACACGCAGATATATATGCCCTTGATCCAGTCAGCAG
Seq A exon
ATAAACGAGAGCACTAGGGCATCTCGCGATTGTCACCGTACACACAGAATAACCCAGATCAGCAGTCATGCCGAAAGATGGTCACTCACGTAAGCCACAAAAGAGGGCGTCCATCGCAGAGGAAACTCCTGTCTCCGATTCCACAACTCCAGCCACAACAGCATCACCCAGCTCACCCAGCAGAACTGCTGGCCACTCCACCATCGGTGCTTTGGTCAGCAACCTGCACCACCATGACATTCAGTCCCTGCATCAACCACTGCTGGAGAGCGAGGAGCGGGTGATAGTCGCGGTTAACCACAGGAATCCTCGCCAGCCACATCGGAGTTATGGGACCGAGCGGAAGCCGCACAGTTCCCTGCCCCGTTTCGTGATCAACATTGAGGAGGAGACGGATGCAGCGGTGGCTGCGGCTGAGGGAAAGAGCAGTCCCGCTCCTAACCAGGAGCACGAGGAGCACTCCAACCAGAGTCCTTCCCGCCGTTTCAGTCACTTCAATCTGGCCCTGCGTCGCTTCTCCCACATCCATGCCCAC
Seq C2 exon
AACATAAATCGCTTCGGAGACTCCATGGGTTCGCTGGGACATCGTGCCTTGTTGCAGTACATCGATAATAATGATATATCCGGTCTGCGCGCCATTTTGGACAGCCGACATCTTACCATCGATGATCGGGACGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261554_CASSETTE1
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. ATG)
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.859 C2=0.035
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
PF127962=Ank_2=PU(29.8=75.7)
Main Inclusion Isoform:
FBpp0310601
Main Skipping Isoform:
FBpp0291847
Other Inclusion Isoforms:
FBpp0310600
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCGACGTTTCAGTTGGCACC
R:
TGGTAAGATGTCGGCTGTCCA
Band lengths:
346-881
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)