DmeEX0004714 @ dm6
Exon Skipping
Gene
FBgn0264562 | Hr4
Description
The gene Hormone receptor 4 is referred to in FlyBase by the symbol DmelHr4 (CG43934, FBgn0264562). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (8 unique). Gene sequence location is X:1941940..2007956. Its molecular function is described by: steroid hormone receptor activity; nuclear receptor activity; zinc ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with 7 unique terms, many of which group under: cellular response to chemical stimulus; regulation of developmental process; negative regulation of RNA metabolic process; prepupal development; negative regulation of cellular response to alcohol. 73 alleles are reported. The phenotypes of these alleles manifest in: embryo; eye; somatic cell; ommatidium; head. The phenotypic classes of alleles include: size defective; lethal - all die before end of pupal stage; phenotype; some die during P-stage.
Coordinates
chrX:1941940-1942893:+
Coord C1 exon
chrX:1941940-1942004
Coord A exon
chrX:1942081-1942161
Coord C2 exon
chrX:1942427-1942893
Length
81 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTGTTGCCTCTCCAGGAT
3' ss Score
10.7
5' ss Seq
AAGGTGCAC
5' ss Score
4.22
Exon sequences
Seq C1 exon
GTGTATCCCACGAGCTAGTCGCGCGCGGAAAGCAAACGCTTCGAAAATCAAACGATATTTCCGTT
Seq A exon
GATTTTGTTGACCATCGTAGATTGGATATGTGAAACAAATTTTAAGGGCCTCCACTTTCTCTATCTCGCCCTAGCAGCAAG
Seq C2 exon
TTGACGTTTAACCCCCACCCACCCAAATAAAGCAAATCTAACTAAAGAGTCCTGCAAAAAAATCAACAGCTGCTTGATCTTGAAGCCTCCATATCTTGAAATCCTGCATCAGCCAACAGCCCCAAAACAAAACAAAACAAAACGAATGCAAATACACTAATGTGAACAACAACTAAATTGCTAGTGAAATGTTTTAAGCCAAATGCTGTGAGTGTGTAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAGAAGAGTGATTCAAAGCAACCGCAAGCAATCAACTTGTAACGGTAGTCGGATACTCGCTTGCCCGCGGAGCATGGATATCGCCCCAGTTCCGCCACCACCATTATCGATATCCGTATCGCTTTCGGCTCCAGGATCAACGGTATTCGCAAACGCTGGCCACTAGAGAAGCGTCAGCCGAATGCCTCAAAGATGACACCGCTGCAACGGGACCAATTGAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0264562_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.900
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCAAACGCTTCGAAAATCAA
R:
TTTTGTTTTGGGGCTGTTGGC
Band lengths:
167-248
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)