DmeEX0007064 @ dm6
Exon Skipping
Gene
FBgn0263603 | Zn72D
Description
The gene Zinc-finger protein at 72D is referred to in FlyBase by the symbol Dmel�n72D (CG5215, FBgn0263603). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is 3L:16106594..16112626. Its molecular function is described by: single-stranded RNA binding; double-stranded RNA binding; zinc ion binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. 13 alleles are reported. The phenotypes of these alleles manifest in: spermatid; spermatozoon; sperm individualization complex; trichogen cell. The phenotypic classes of alleles include: lethal - all die during P-stage; lethal; increased mortality during development; phenotype.
Coordinates
chr3L:16107596-16110122:-
Coord C1 exon
chr3L:16109622-16110122
Coord A exon
chr3L:16108852-16109054
Coord C2 exon
chr3L:16107596-16107786
Length
203 bp
Sequences
Splice sites
3' ss Seq
AACGTATTTGCCGTTTTCAGCTT
3' ss Score
8.05
5' ss Seq
ACGGTAACA
5' ss Score
6.72
Exon sequences
Seq C1 exon
TGCCCAGCGCTTTGGGCGCATGGGCAATGGACCGCCGCCGCACTTTGGCATGATGCCCGGCGGAAATGTTCGTCGTCCGGAAAGCACCGATGATCGCCACGCCATTGCCCGTCACGCCGAGATCTATCCGAAGGAGGAGGAGCTGCAGACCATCCAGCGCATCGTCTCGCACACCGAGAGGGCCCTAAAATTGGTCTCCGATGCCCTGGCCGAGCAGCCCAGCGATGCCGGAGCGGCCAATAAGAAGGACAAGGCTGAAAAGCCGTCGGAGAAAGACGGACGCGACAATCAGATCTTCTCGTTCCAAAAAGACGCCGACAATGGTGGCAATGTCGTGCGCATCCTGAAGGGAGTGATGCGAGTGGGCTACCTGGCCAAGGGGCTGCTGCTCCACGGCGACAACGCCGTCGAGCTGGTCGTCCTTTGCGCGGAGAAGCCGACTTCGGGTCTTTTGCAGCGTGTGGCCAATGTGCTGCCCGACAAACTCAAGGAGGTGGCAG
Seq A exon
CTTCTCTCTCTGCAGGATAAGTTTCGAGCCTCGAGCCTTGAGCCTTAGCCTAGAAGCTCTGTGAGCCTAGAGTCTTGAGTGTGTCGTTCAGTTAGCCATCTGTAGCGGTAGCTCAGCCCTCCCAGGTTGCTCCTCTTCCCGCACGACTGCCGCTGCACTGCTCCGCTCCACTCCAATCAAATCACCAACAGCGGATCGTCACG
Seq C2 exon
GCGACACTCAGGTCAATTACCGCGTGGAGGTCAACGCCGAGGAAGCCGCCCTAATTGTGCTGGATGAGTCTGTCTCCGTTAAGATTACCCTCACCTCGCCTTTGCTGCGCGATGCCAATCCCGGGGAAGCTGCCACCACTGATGAAGGTGAGGGCGATTCCGAATTCCTGCCTCGTGAGCCCTGCCTACGT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263603_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.520 A=0.000 C2=0.274
Domain overlap (PFAM):
C1:
PF075289=DZF=PU(92.2=28.0)
A:
PF075289=DZF=PD(5.9=42.9)
C2:
PF075289=DZF=FE(25.5=100)
Main Inclusion Isoform:
FBpp0075248
Main Skipping Isoform:
FBpp0075249
Other Inclusion Isoforms:
FBpp0305488
Other Skipping Isoforms:
FBpp0302718, FBpp0302719, FBpp0305489
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGCGGCCAATAAGAAGGAC
R:
GTTGACCTCCACGCGGTAATT
Band lengths:
306-509
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)