DmeINT0029494 @ dm6
Intron Retention
Gene
FBgn0263603 | Zn72D
Description
The gene Zinc-finger protein at 72D is referred to in FlyBase by the symbol Dmel�n72D (CG5215, FBgn0263603). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is 3L:16106594..16112626. Its molecular function is described by: single-stranded RNA binding; double-stranded RNA binding; zinc ion binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. 13 alleles are reported. The phenotypes of these alleles manifest in: spermatid; spermatozoon; sperm individualization complex; trichogen cell. The phenotypic classes of alleles include: lethal - all die during P-stage; lethal; increased mortality during development; phenotype.
Coordinates
chr3L:16108852-16110122:-
Coord C1 exon
chr3L:16109622-16110122
Coord A exon
chr3L:16109055-16109621
Coord C2 exon
chr3L:16108852-16109054
Length
567 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGT
5' ss Score
10.86
3' ss Seq
AACGTATTTGCCGTTTTCAGCTT
3' ss Score
8.05
Exon sequences
Seq C1 exon
GTGCCCAGCGCTTTGGGCGCATGGGCAATGGACCGCCGCCGCACTTTGGCATGATGCCCGGCGGAAATGTTCGTCGTCCGGAAAGCACCGATGATCGCCACGCCATTGCCCGTCACGCCGAGATCTATCCGAAGGAGGAGGAGCTGCAGACCATCCAGCGCATCGTCTCGCACACCGAGAGGGCCCTAAAATTGGTCTCCGATGCCCTGGCCGAGCAGCCCAGCGATGCCGGAGCGGCCAATAAGAAGGACAAGGCTGAAAAGCCGTCGGAGAAAGACGGACGCGACAATCAGATCTTCTCGTTCCAAAAAGACGCCGACAATGGTGGCAATGTCGTGCGCATCCTGAAGGGAGTGATGCGAGTGGGCTACCTGGCCAAGGGGCTGCTGCTCCACGGCGACAACGCCGTCGAGCTGGTCGTCCTTTGCGCGGAGAAGCCGACTTCGGGTCTTTTGCAGCGTGTGGCCAATGTGCTGCCCGACAAACTCAAGGAGGTGGCAG
Seq A exon
GTAAGTGAGGAGATGTGGCAGCTGCCATCGTAGAAATTGCATACCACTATTCTTGAATGACATTTTGGTTGTCCTAATGAGAGGAACAGAATAGAACTTTTTCCAGAGAAATGGCTTGAGTGATAAATGCGGCTGAAAAGCATCACTGAATCATGATCAAAACAAAAAGTACATTAACACGTTCTTAGCTTGGCCAATTTCACACTGACCTGCGCAGGTGAATTTGGCCAAATTGGAAGCGGCTCAAACTAATCAACTAAAACTAATGAACGAAAATAAATCGATTTTCGGAGCGCTAAATATGCAAGATGAACGAACGCAACTCACGATACGTTCGCATTCGCTATTCATTACGTACGTTCACGTTCGACGGGCAATTTGTGTGGAAAAAGTCAGCAAAATAAATCAAATTTAACTATTTAAAATTATTGTACATAGAAACTAGGACAACTAGAGTTGAGCCCTGTTGTTGCGGTGGATATAGATTGCCACGCCCGCCAAACCGCGCCCAACGCCCCAGCCAACATAGCAACTAATTGCGAATAAAAACGTATTTGCCGTTTTCAG
Seq C2 exon
CTTCTCTCTCTGCAGGATAAGTTTCGAGCCTCGAGCCTTGAGCCTTAGCCTAGAAGCTCTGTGAGCCTAGAGTCTTGAGTGTGTCGTTCAGTTAGCCATCTGTAGCGGTAGCTCAGCCCTCCCAGGTTGCTCCTCTTCCCGCACGACTGCCGCTGCACTGCTCCGCTCCACTCCAATCAAATCACCAACAGCGGATCGTCACG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263603:FBtr0075493:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.520 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF075289=DZF=PU(92.2=28.0)
A:
NA
C2:
PF075289=DZF=PD(5.9=42.9)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0075248
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGAAGGGAGTGATGCGAGTG
R:
GACGATCCGCTGTTGGTGATT
Band lengths:
357-924
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)