DmeEX0007723 @ dm6
Exon Skipping
Gene
FBgn0053196 | dp
Description
The gene dumpy is referred to in FlyBase by the symbol Dmeldpy (CG33196, FBgn0053196). It is a protein_coding_gene from Dmel. It has 17 annotated transcripts and 17 polypeptides (16 unique). Gene sequence location is 2L:4477462..4614300. Its molecular function is described by: zinc ion binding; DNA-binding transcription factor activity; extracellular matrix structural constituent; calcium ion binding. It is involved in the biological process described with 6 unique terms, many of which group under: cuticle development; RNA biosynthetic process; chitin-based cuticle attachment to epithelium; chitin-based embryonic cuticle biosynthetic process; regulation of cellular macromolecule biosynthetic process. 332 alleles are reported. The phenotypes of these alleles manifest in: epidermal cell; cephalic branch; mesothoracic tergum; adult abdomen; adult trachea. The phenotypic classes of alleles include: increased mortality during development; phenotype; modifier of variegation; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr2L:4532243-4552335:-
Coord C1 exon
chr2L:4552243-4552335
Coord A exon
chr2L:4540442-4546933
Coord C2 exon
chr2L:4532243-4532386
Length
6492 bp
Sequences
Splice sites
3' ss Seq
ACCCTGAAATTTTGAAGCAGCTA
3' ss Score
1.94
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
Exon sequences
Seq C1 exon
GTTACTTGACTACGCCGAAGCAGGATTGTCGTACCCTTGGATGCGAAGTCGGCGGCTGTGTACGCCAGGGCTATGAATACGTTTGCCAGCAGG
Seq A exon
CTAAGCCAGGTGGAAACTGTACGTCAAACACAGATTGCAGTCAAGCGCACCAATGTGGATCGTCGGGAAAATGTATCGACCCCTGCCTCACTTCCTGTGCAGGCGGAGTAAAGTGTGTTGTATCAGCACATAGGGTTACTATATGTACTTGTCCAGCCACCTTAACAAACAACACAGATTCGAACTGCACCTCGACAGACATAACAGTCGGGACTACAACGCAAAGAATTGAAACTACAACAGACTTCATTAACGTAAAATACACTGTAATGCAATTGGCAAATCAAACTGAAATGAGAACCCGCTTTACCGATATAGAAGCCGAAAACGAAACAACAGGTCCTTACACAACCACAACAGAGTCCTATAAGACGACTAAGCAACTTTCTTCTAACCCAGAAACAGAGACACCCACAACTTTACCTTCACGCCCAACAACTAGACCATTTACTGATCAAACGACTGAATTTACTAGTGAAATTCCCACTATCACACCAATGGAGGGATCTACTCCCACACCATCACATCTAGAAACCACTGTCGCATCAATCACCTCAGAATCCACTACCAGAGAAGTATATACCATCAAGCCCTTCGATAGATCTACTCCCACTCCAGTATCGCCGGACACTACTGTTCCATCAATCACTTTTGAAACCACCACAAATATTCCGATTGGAACAACACGAGGGCAAGTGACAGAACAGACTACATCTTCTCCCAGCGAAAAGAGAACTACAATACGTGTTGAAGAATCTACACTTCCTTCTAGGTCAACGGATAGAACCACTCCATCCGAAAGTCCTGAGACACCCACAATATTACCTTCAGACTCCACTACTCGAACTTACTCAGATCAAACGACTGAATCTACTAGAGACGTTCCAACCACCCGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACAACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGATCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTCAGAACTACAATAGGTCTTGAAGAATCTACACTTCCTTCAAGGTCAACGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCATAACTAGACCTCACTCAGATCAAACGACTGAATCTACTAGAGACGTTCCAACCACCCGCCCATTTGAGGCATCTACTCCCAGTTCAGCATCTCTGGAAACAACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTGAGAACTACAATACGCGTTGAAGAATCTACACTTCCTTCAAGGTCAGCGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCAACAACATTACCTTCAGACTTCACAACTAGACCTCACTCAGAACAAACAACTGAATCTACTAGAGACGTTCCAACCACCCGCCCATTTGAGGCATCCACTCCCAGTCCAGCATCTCTGGAAACAACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGGACAAACTACATCTTCTCCGAGCGAAGTGAGAACTACAATACGCGTTGAAGAATCTACACTTCCTTCAAGGTCAGCGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCATAACTAGACCTCACTCAGAAAAAACAACTGAATCTACCAGAGACGTTCCAACCACCCGCCCATTTGAGGCATCTACTCCCAGTTCAGCATCTCTGGAAACAACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTCAGAACTACAATACGTGTTGAAGAATCTACACTTCCTTCAAGGTCAGCGGATAGAACTACTCTATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCACAATTAGACCTCACTCAGAACAAACGACTGAATCAACTAGAGACGTTCCAACCACCAGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACTACTGTTCCATCAGTCACTTCAGAAACCACTACAAATGTTCCAATTGGTTCAACAGGTGGGCAAGTGACAGGACAGACTACTGCACCGCCGAGCGAATTCAGAACTACAATACGTGTTGAAGAATCTACACTTCCTTCTAGGTCAACGGATAGAACCACTCCATCCGAAAGTCCTGAGACACCCACAATATTACCTTCAGACTCCACTACTCGAACTTACTCAGATCAAACGACTGAATCTACTAGAGACGTTCCAACCACCCGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACAACTGTTCCATCGGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTGAGAACTACAATACGCGTTGAAGAATCTACACTTCCTTCAAGGTCAGCGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCATAACTAGACCTCACTCAGAAAAAACAACTGAATCTACCAGAGACGTTCCAACCACCCGCCCATTTGAGGCATCTACTCCCAGTTCAGCATCTCTGGAAACAACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTGAGAACTACAATACGCGTTGAAGAATCTACACTTCCTTCAAGGTCAGCGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCATAACTAGACCTCACTCAGAAAAAACAACTGAATCTACCAGAGACGTTCCAACCACCCGCCCATTTGAGGCATCTACTCCCAGTTCAGCATCTCTGGAAACAACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTCAGAACTACAATACGTGTTGAAGAATCTACACTTCCTTCAAGGTCAACGGATAGAACTACTCCATCCGAAAGTCCTGAAACACCAACAACATTACCTTCAGACTTCACAACTAGACCTCACTCAGAACAAACGACTGAATCTACTAGAGACGTTCCAACCACCCGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACAACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTCAGAACTACAATACGTGTTGAAGAATCTACACTTCCTTCAAGGTCAGCGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCATAACTCGAACTTACTCAGATCAAACGACTGAATCTACTAGAGACGTTCCAACCACCCGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACTACTGTTCCATCAGTCACTTCAGAAACCACTACAAATGTTCCAATTGGTTCAACAGGTGGGCAAGTGACAGGACAGACTACTGCACCGCCGAGCGAATTCAGAACTACAATACGTGTTGAAGAATCTACACTTCCTTCAAGGTCAACGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCACAACTAGACCTCACTCAGATCAAACGACTGAATCTACTAGAGACGTTCCAACCACCAGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACTACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTGAGAACTACAATACGCGTTGAAGAATCTACACTTCCTTCAAGGTCAGCGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCAACATTACCTTCAGACTTCACAACTAGACCTCACTCAGAACAAACGACTGAATCTACTAGAGACGTTCCGGCCACCAGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACTACTGTTCCATCAGTCACTTCAGAAGCCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTCAGAACTACAATACGTGTTGAAGAATCTACACTTCCTTCAAGGTCAACGGATAGAACTTCTCCATCCGAAAGTCCTGAAACACCAACAACATTACCTTCAGACTTCACAACTAGACCTCACTCAGATCAAACGACTGAATGTACTAGAGACGTTCCAACCACCCGCCCATTTGAGGCATCTACTCCCAGTTCAGCATCTCTGGAAACAACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTGAGAACTACAATACGCGTTGAAGAATCTACACTTCCTTCAAGGTCAGCGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCAACATTACCTTCAGACTTCACAACTAGACCTCACTCAGAACAAACGACTGAATCTACTAGAGACGTTCCAACCACCAGGCCATTTGAGGCATCTACTCCCAGTTCAGCATCTCTGGAAACAACTGTTCCATCAGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAATTCAGAACTACAATACGCGTTGAAGAATCTACACTTCCTTCAAGGTCAGCGGATAGAACTACTCCATCCGAAAGTCCTGAGACACCAACATTACCTTCAGACTTCACAACTAGACCTCACTCAGAACAAACGACTGAATCTACTAGAGACGTTCCAACCACCAGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACTACTGTTCCATCAGTCACTTCAGAAACCACTACAAATGTTCCAATTGGTTCAACAGGTGGGCAAGTGACAGGACAGACTACTGCACCGCCGAGCGAAGTCAGAACTACAATACGTGTTGAAGAATCTACACTTCCTTCTAGGTCAACGGATAGAACCACTCCATCCGAAAGTCCTGAGACACCCACAATATTACCTTCAGACTCCACTACTCGAACTTACTCAGATCAAACGACTGAATCTACTAGAGACGTTCCAACCACCCGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACAACTGTTCCATCGGTTACTTTAGAAACCACTACAAATGTTCCAATCGGTTCAACAGGTGGGCAAGTGACAGGACAGACTACTGCAACGCCGAGCGAAGTCAGAACTACAATAGGTGTTGAAGAATCTACACTTCCTTCAAGGTCAACGGATAGAACTTCTCCATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCACAACTAGACCTCACTCAGATCAAACGACTGAATCAACTAGAGACGTTCCAACCACCCGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACTACTGTTCCATCAGTCACTTCAGAAACCACTACAAATGTTCCAATTGGTTCAACAGGTGGGCAAGTGACAGAACAAACTACATCTTCTCCGAGCGAAGTCAGAACTACAATAGGTCTTGAAGAATCTACACTTCCTTCAAGGTCAACGGATAGAACTTCTCCATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCATAACTAGACCTCACTCAGATCAAACGACTGAATCTACTAGAGACGTTCCAACCACCAGGCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGGAAACTACTGTTCCATCAGTCACTTCAGAAACTACTACAAATGTTCCAATTGGTTCAACAGGTGGGCAAGTGACAGGACAGACTACTGCACCGCCGAGCGAAGTCAGAACTACAATAGGTGTTGAAGAATCTACACTTCCTTCAAGGTCAACGGATAGAACTTCTCCATCCGAAAGTCCTGAGACACCCACAACATTACCTTCAGACTTCATAACTAGACCTCACTCAGAACAAACGACTGAATCTACTAGAGACGTTCCAACCACCCGTCCATTTGAGGCATCTACTCCCAGTCCAGCATCTCTGAAAACAACTGTTCCATCAGTCACTTCAGAAGCCACTACAAATGTTCCAATCGGTTCAACAG
Seq C2 exon
AGATTGGATGCGCATCGAGTGATGAGTGTCCGTCCCAGCAGGCGTGCATTAATGCTCTTTGTGTGGATCCTTGCACCTTTAACAATCCCTGCAGCCGTAATGAAGATTGCCGAGTTTTTAACCACCAGCCATTGTGCTCAGCCG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0053196_MULTIEX3-2/6=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=80%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.958 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0304622
Main Skipping Isoform:
FBpp0304630
Other Inclusion Isoforms:
FBpp0293671, FBpp0293672, FBpp0304620, FBpp0304621, FBpp0304623, FBpp0304625, FBpp0304626, FBpp0304627, FBpp0304628, FBpp0304629, FBpp0304632
Other Skipping Isoforms:
FBpp0293675, FBpp0304624, FBpp0304631
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)