Special

FBgn0053196 @ dm6

Biotype
protein_coding
Gene Symbol
dp
Description
The gene dumpy is referred to in FlyBase by the symbol Dmeldpy (CG33196, FBgn0053196). It is a protein_coding_gene from Dmel. It has 17 annotated transcripts and 17 polypeptides (16 unique). Gene sequence location is 2L:4477462..4614300. Its molecular function is described by: zinc ion binding; DNA-binding transcription factor activity; extracellular matrix structural constituent; calcium ion binding. It is involved in the biological process described with 6 unique terms, many of which group under: cuticle development; RNA biosynthetic process; chitin-based cuticle attachment to epithelium; chitin-based embryonic cuticle biosynthetic process; regulation of cellular macromolecule biosynthetic process. 332 alleles are reported. The phenotypes of these alleles manifest in: epidermal cell; cephalic branch; mesothoracic tergum; adult abdomen; adult trachea. The phenotypic classes of alleles include: increased mortality during development; phenotype; modifier of variegation; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr2L:4477462-4614300:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
357
chr2L:4563111-4563467
-
34.86
100
0
Exon Skipping
7278
chr2L:4555206-4562483
-
82.23
78.49
0
Exon Skipping
486
chr2L:4529792-4530277
-
93.87
57.25
0
Exon Skipping
327
chr2L:4523031-4523357
-
26.09
78.25
0
Exon Skipping
324
chr2L:4522641-4522964
-
50.78
98.94
0
Exon Skipping
630
chr2L:4521813-4522442
-
49.4
100
0
Exon Skipping
339
chr2L:4521417-4521755
-
50.78
100
0
Exon Skipping
309
chr2L:4521043-4521351
-
50
100
0
Exon Skipping
327
chr2L:4520377-4520703
-
50.06
99.59
0
Exon Skipping
1590
chr2L:4518710-4520299
-
95.06
44.26
0
Exon Skipping
3192
chr2L:4515397-4518588
-
95.96
34.92
0
Exon Skipping
327
chr2L:4513435-4513761
-
20.95
68.54
0
Exon Skipping
321
chr2L:4513056-4513376
-
24.8
100
0
Exon Skipping
2433
chr2L:4527296-4529728
-
93.28
65.11
0
Exon Skipping
345
chr2L:4512650-4512994
-
23.67
100
0
Exon Skipping
297
chr2L:4512290-4512586
-
21
67.72
0
Exon Skipping
303
chr2L:4511933-4512235
-
15.65
63.56
0
Exon Skipping
648
chr2L:4511231-4511878
-
20.21
66.09
0
Exon Skipping
318
chr2L:4510859-4511176
-
23.6
67.68
0
Exon Skipping
336
chr2L:4510466-4510801
-
22.41
70.77
0
Exon Skipping
615
chr2L:4509782-4510396
-
24.38
73.12
0
Exon Skipping
645
chr2L:4509082-4509726
-
24.68
73.01
0
Exon Skipping
312
chr2L:4508713-4509024
-
25.94
77.65
0
Exon Skipping
339
chr2L:4508311-4508649
-
24.73
82.85
0
Exon Skipping
624
chr2L:4526606-4527229
-
94.91
58.54
0
Exon Skipping
309
chr2L:4507939-4508247
-
24.36
76.78
0
Exon Skipping
945
chr2L:4506934-4507878
-
27.41
76.7
0
Exon Skipping
312
chr2L:4506559-4506870
-
29.8
88.58
0
Exon Skipping
345
chr2L:4506154-4506498
-
31.14
92.23
0
Exon Skipping
300
chr2L:4505794-4506093
-
30.29
84.36
0
Exon Skipping
951
chr2L:4504777-4505727
-
27.86
78.63
0
Exon Skipping
318
chr2L:4504354-4504671
-
12.85
70.33
0
Exon Skipping
333
chr2L:4503958-4504290
-
13.3
68.31
0
Exon Skipping
315
chr2L:4503585-4503899
-
14.66
65.31
0
Exon Skipping
306
chr2L:4503221-4503526
-
14.53
72.32
0
Exon Skipping
318
chr2L:4526224-4526541
-
95.14
55.26
0
Exon Skipping
648
chr2L:4502517-4503164
-
14.14
72.43
0
Exon Skipping
312
chr2L:4502140-4502451
-
18.68
87.52
0
Exon Skipping
339
chr2L:4501726-4502064
-
16.66
69.56
0
Exon Skipping
1263
chr2L:4500404-4501666
-
14.9
52.59
0
Exon Skipping
315
chr2L:4500025-4500339
-
14.5
89.03
0
Exon Skipping
1599
chr2L:4498362-4499960
-
13.53
62.72
0
Exon Skipping
315
chr2L:4497984-4498298
-
14.67
64.79
0
Exon Skipping
648
chr2L:4497276-4497923
-
13.99
70.88
0
Exon Skipping
963
chr2L:4496247-4497209
-
12.85
56.23
0
Exon Skipping
1989
chr2L:4494171-4496159
-
3.38
26.48
0
Exon Skipping
324
chr2L:4525604-4525927
-
26.79
79.9
0
Exon Skipping
306
chr2L:4493799-4494104
-
5.02
89.64
0
Exon Skipping
3345
chr2L:4490376-4493720
-
4.41
41.37
0
Exon Skipping
651
chr2L:4489668-4490318
-
4.39
53.81
0
Exon Skipping
660
chr2L:4488454-4489113
-
36.98
100
0
Exon Skipping
939
chr2L:4487449-4488387
-
42.07
100
0
Exon Skipping
1686
chr2L:4485508-4487193
-
97.64
24.2
0
Exon Skipping
318
chr2L:4525087-4525404
-
29.53
100
0
Exon Skipping
333
chr2L:4524691-4525023
-
24.04
81.18
0
Exon Skipping
327
chr2L:4524298-4524624
-
26.09
77.5
0
Exon Skipping
318
chr2L:4523752-4524069
-
26.98
79.41
0
Exon Skipping
798
chr2L:4548005-4548802
-
58.46
74.78
0
Exon Skipping
6492
chr2L:4540442-4546933
-
5.16
20.55
0
Exon Skipping
1404
chr2L:4533571-4534974
-
8.78
34
0
Exon Skipping
618
chr2L:4531353-4531970
-
33.11
99.73
0
Exon Skipping
222
chr2L:4530832-4531053
-
64.5
86.34
0
Intron Retention
1071
chr2L:4546934-4548004
-
11.06
59.85
0
Intron Retention
118
chr2L:4530714-4530831
-
3.5
52.59
0
Intron Retention
5924
chr2L:4520300-4526223
-
6.03
38.02
0
Intron Retention
1635
chr2L:4513762-4515396
-
4.13
52.66
0
Intron Retention
61
chr2L:4512995-4513055
-
3.39
52.54
0
Intron Retention
63
chr2L:4512587-4512649
-
5.13
80.48
0
Intron Retention
63
chr2L:4508248-4508310
-
2.63
52.39
0
Intron Retention
212
chr2L:4563468-4563679
-
5.52
82.95
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000049323 LTBP1 1-to-4
Human hg38 ENSG00000090006 LTBP4 1-to-4
Human hg38 ENSG00000119681 LTBP2 1-to-4
Human hg38 ENSG00000168056 LTBP3 1-to-4
Human hg19 ENSG00000049323 LTBP1 1-to-4
Human hg19 ENSG00000090006 LTBP4 1-to-4
Human hg19 ENSG00000119681 LTBP2 1-to-4
Human hg19 ENSG00000168056 LTBP3 1-to-4
Mouse mm10 ENSMUSG00000001870 Ltbp1 1-to-4
Mouse mm10 ENSMUSG00000002020 Ltbp2 1-to-4
Mouse mm10 ENSMUSG00000024940 Ltbp3 1-to-4
Mouse mm10 ENSMUSG00000040488 Ltbp4 1-to-4
Mouse mm9 ENSMUSG00000001870 Ltbp1 1-to-4
Mouse mm9 ENSMUSG00000002020 Ltbp2 1-to-4
Mouse mm9 ENSMUSG00000024940 Ltbp3 1-to-4
Mouse mm9 ENSMUSG00000040488 Ltbp4 1-to-4
Rat rn6 ENSRNOG00000007302 Fbn1 1-to-2
Rat rn6 ENSRNOG00000043219 Fbn2 1-to-2
Cow bosTau6 ENSBTAG00000004757 LTBP4 1-to-4
Cow bosTau6 ENSBTAG00000006747 LTBP3 1-to-4
Cow bosTau6 ENSBTAG00000019839 LTBP1 1-to-4
Cow bosTau6 ENSBTAG00000021957 LTBP2 1-to-4
Chicken galGal4 ENSGALG00000010258 LTBP2 1-to-2
Chicken galGal4 ENSGALG00000010448 LTBP1 1-to-2
Chicken galGal3 ENSGALG00000010258 LTBP2 1-to-2
Chicken galGal3 ENSGALG00000010448 LTBP1 1-to-2
Zebrafish danRer10 ENSDARG00000035682 ltbp3 1-to-4
Zebrafish danRer10 ENSDARG00000056922 ltbp1 1-to-4
Zebrafish danRer10 ENSDARG00000097768 ltbp1 1-to-4
Zebrafish danRer10 ENSDARG00000099137 LTBP4 1-to-4