DmeINT0031211 @ dm6
Intron Retention
Gene
FBgn0053196 | dp
Description
The gene dumpy is referred to in FlyBase by the symbol Dmeldpy (CG33196, FBgn0053196). It is a protein_coding_gene from Dmel. It has 17 annotated transcripts and 17 polypeptides (16 unique). Gene sequence location is 2L:4477462..4614300. Its molecular function is described by: zinc ion binding; DNA-binding transcription factor activity; extracellular matrix structural constituent; calcium ion binding. It is involved in the biological process described with 6 unique terms, many of which group under: cuticle development; RNA biosynthetic process; chitin-based cuticle attachment to epithelium; chitin-based embryonic cuticle biosynthetic process; regulation of cellular macromolecule biosynthetic process. 332 alleles are reported. The phenotypes of these alleles manifest in: epidermal cell; cephalic branch; mesothoracic tergum; adult abdomen; adult trachea. The phenotypic classes of alleles include: increased mortality during development; phenotype; modifier of variegation; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr2L:4507939-4508649:-
Coord C1 exon
chr2L:4508311-4508649
Coord A exon
chr2L:4508248-4508310
Coord C2 exon
chr2L:4507939-4508247
Length
63 bp
Sequences
Splice sites
5' ss Seq
AAAGTAAGA
5' ss Score
6.91
3' ss Seq
CATACATTTTAATAAATCAGTTC
3' ss Score
2.92
Exon sequences
Seq C1 exon
CTCCGCCTCCAGTTGTCGAACGTGAACCCCTTGACCCTTGTGTTCCTTCACCCTGCGGTGCAAATTCCCAGTGCCGCGAAATTCACGGCACACCATCCTGCTCTTGCCTTCCGCAATATTTGGGTACACCACCCAATTGCCGCCCGGAATGTTCCATCAATGCCGAGTGTCCCAGTCATCAGGCCTGTATTAATCAAAAATGCAGAGACCCCTGTCCTGGCTCTTGTGGTCTAAACACTCAGTGCAGTGTCATCAACCACACGCCAATCTGCAGTTGTCTCGCGGGTTATATAGGTGACCCATTCAGCGTTTGCAACCCCGAGCCAATACCCGAGAAAA
Seq A exon
GTAAGATGCATTATCTACCAAGGCTAAAGCTCAAAAATCATAACATACATTTTAATAAATCAG
Seq C2 exon
TTCGAGACCCACTGCCACCGGAGGATCCTTGCAACCCATCACCATGTGGCTCTAATACACAGTGCAACAATGGAGTTTGCTCTTGCCTGCCCGAATACCATGGTGACCCATACACGGGATGTCGTCCAGAGTGCGTTCTGCACACGGATTGTGACCGTAGTAGAGCTTGTGTTCGTCACAAGTGTGTTGATCCCTGTCCCGGTACTTGTGGAACCAATGCGATATGCGAGGTTCTAAACCATATACCCAACTGCCGTTGTTTAGAAGGAATGCAAGGCAATGCATTTATCCAGTGCAGCCCAGTTCCAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0053196:FBtr0332355:39
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.029
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0304622
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0304620, FBpp0304623, FBpp0304624, FBpp0304625, FBpp0304626, FBpp0304627, FBpp0304628, FBpp0304630, FBpp0304631, FBpp0304632
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCATCAACCACACGCCAAT
R:
TAGAGCCACATGGTGATGGGT
Band lengths:
146-209
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)