DmeEX0009775 @ dm6
Exon Skipping
Gene
FBgn0003654 | sw
Description
The gene short wing is referred to in FlyBase by the symbol Dmelsw (CG18000, FBgn0003654). It is a protein_coding_gene from Dmel. It has 16 annotated transcripts and 16 polypeptides (12 unique). Gene sequence location is X:20227961..20236382. Its molecular function is described by: dynein light chain binding; dynactin binding; dynein heavy chain binding. It is involved in the biological process described with 11 unique terms, many of which group under: cellular process; organelle organization; microtubule-based process; movement of cell or subcellular component; protein localization to organelle. 37 alleles are reported. The phenotypes of these alleles manifest in: anterior-posterior subdivision of organism; organism subdivision; tagma; anatomical structure; organ system subdivision. The phenotypic classes of alleles include: lethal - all die before end of larval stage; increased mortality during development; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed in adult male stages.
Coordinates
chrX:20230441-20233443:-
Coord C1 exon
chrX:20233423-20233443
Coord A exon
chrX:20232117-20232164
Coord C2 exon
chrX:20230441-20230634
Length
48 bp
Sequences
Splice sites
3' ss Seq
TTTCTTTATATTTCTTCAAGATG
3' ss Score
6.66
5' ss Seq
CAGGTAGGT
5' ss Score
10.28
Exon sequences
Seq C1 exon
CTCATGCTACGGATTATTATG
Seq A exon
ATGAATACAATCTTAATCCGGGTTTAGAGTGGGAGGATGAATTCACAG
Seq C2 exon
TTTTATACCTTAAACAGTGCTTGCATTTGATGCCCAAGGAGACGACGAAGAGAGCTCACTGCAGAACCTGGGCAACGGATTCACCTCCAAGCTGCCACCGGGCTATCTCACCCACGGCCTGCCCACCGTTAAGGACGTCGCCCCGGCCATCACACCACTCGAGATCAAGAAGGAGACTGAAGTGAAGAAGGAGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0003654-'9-10,'9-9,10-10
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.636 A=0.647 C2=0.607
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0088428
Main Skipping Isoform:
FBpp0088419
Other Inclusion Isoforms:
FBpp0088422, FBpp0088423, FBpp0088424, FBpp0088425, FBpp0088426, FBpp0088429, FBpp0089020, FBpp0089021, FBpp0309319
Other Skipping Isoforms:
FBpp0088420, FBpp0088421, FBpp0309318
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)