DmeINT0005998 @ dm6

FBgn0033783 | CG17019

This gene is referred to in FlyBase by the symbol DmelCG17019 (FBgn0033783). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:12930912..12934045. Its molecular function is described by: ubiquitin protein ligase activity; zinc ion binding. It is involved in the biological process described with: protein K48-linked ubiquitination; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; proteasome-mediated ubiquitin-dependent protein catabolic process; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. 6 alleles are reported. The phenotypes of these alleles manifest in: indirect flight muscle; mitochondrion. The phenotypic classes of alleles include: stress response defective; locomotor behavior defective; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during late pupal stages, in adult female stages.