FBgn0033783 @ dm6
Biotype
protein_coding
Gene Symbol
CG17019
Description
This gene is referred to in FlyBase by the symbol DmelCG17019 (FBgn0033783). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:12930912..12934045. Its molecular function is described by: ubiquitin protein ligase activity; zinc ion binding. It is involved in the biological process described with: protein K48-linked ubiquitination; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; proteasome-mediated ubiquitin-dependent protein catabolic process; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. 6 alleles are reported. The phenotypes of these alleles manifest in: indirect flight muscle; mitochondrion. The phenotypic classes of alleles include: stress response defective; locomotor behavior defective; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during late pupal stages, in adult female stages.
Coordinates
chr2R:12930912-12934045:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000092871 | RFFL | 1-to-3 |
Human | hg38 | ENSG00000170633 | RNF34 | 1-to-3 |
Human | hg19 | ENSG00000092871 | RFFL | 1-to-3 |
Human | hg19 | ENSG00000170633 | RNF34 | 1-to-3 |
Mouse | mm10 | ENSMUSG00000020696 | Rffl | 1-to-2 |
Mouse | mm10 | ENSMUSG00000029474 | Rnf34 | 1-to-2 |
Mouse | mm9 | ENSMUSG00000020696 | Rffl | 1-to-2 |
Mouse | mm9 | ENSMUSG00000029474 | Rnf34 | 1-to-2 |
Rat | rn6 | ENSRNOG00000001331 | Rnf34 | 1-to-2 |
Rat | rn6 | ENSRNOG00000007596 | Rffl | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000002315 | RNF34 | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000013645 | RFFL | 1-to-2 |
Chicken | galGal4 | ENSGALG00000002225 | RFFL | 1-to-2 |
Chicken | galGal4 | ENSGALG00000004190 | RNF34 | 1-to-2 |
Chicken | galGal3 | ENSGALG00000002225 | Q5ZI26_CHICK | 1-to-2 |
Chicken | galGal3 | ENSGALG00000004190 | RNF34 | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000038300 | rnf34a | 1-to-4 |
Zebrafish | danRer10 | ENSDARG00000042833 | rffl | 1-to-4 |
Zebrafish | danRer10 | ENSDARG00000054036 | rnf34b | 1-to-4 |
Zebrafish | danRer10 | ENSDARG00000056244 | RFFL (2 of 2) | 1-to-4 |