DmeINT0019371 @ dm6

FBgn0000157 | Dll

The gene Distal-less is referred to in FlyBase by the symbol DmelDll (CG3629, FBgn0000157). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:24814822..24835667. Its molecular function is described by: sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with 16 unique terms, many of which group under: organic substance biosynthetic process; positive regulation of biological process; nervous system development; central nervous system development; clypeo-labral disc development. 44 alleles are reported. The phenotypes of these alleles manifest in: lobe system of mushroom body; larval maxillary segment sense organ; macrochaeta; hindgut; female genitalia. The phenotypic classes of alleles include: phenotype; increased mortality; increased mortality during development; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.