FBgn0000157 @ dm6
Biotype
protein_coding
Gene Symbol
Dll
Description
The gene Distal-less is referred to in FlyBase by the symbol DmelDll (CG3629, FBgn0000157). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:24814822..24835667. Its molecular function is described by: sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with 16 unique terms, many of which group under: organic substance biosynthetic process; positive regulation of biological process; nervous system development; central nervous system development; clypeo-labral disc development. 44 alleles are reported. The phenotypes of these alleles manifest in: lobe system of mushroom body; larval maxillary segment sense organ; macrochaeta; hindgut; female genitalia. The phenotypic classes of alleles include: phenotype; increased mortality; increased mortality during development; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.
Coordinates
chr2R:24814822-24835667:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000108813 | DLX4 | 1-to-1 |
Human | hg19 | ENSG00000108813 | DLX4 | 1-to-1 |
Mouse | mm10 | ENSMUSG00000020871 | Dlx4 | 1-to-1 |
Mouse | mm9 | ENSMUSG00000020871 | Dlx4 | 1-to-1 |
Rat | rn6 | ENSRNOG00000001520 | Dlx1 | 1-to-3 |
Rat | rn6 | ENSRNOG00000004399 | Dlx4 | 1-to-3 |
Rat | rn6 | ENSRNOG00000010822 | AABR07059679.1 | 1-to-3 |
Cow | bosTau6 | ENSBTAG00000007353 | DLX4 | 1-to-1 |
Zebrafish | danRer10 | ENSDARG00000011956 | dlx4a | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000071560 | dlx4b | 1-to-2 |