DmeINT0020062 @ dm6
Intron Retention
Gene
FBgn0262740 | Evi5
Description
The gene Ecotropic viral integration site 5 is referred to in FlyBase by the symbol DmelEvi5 (CG11727, FBgn0262740). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is X:11430523..11454386. Its molecular function is described by: Rab GTPase binding; GTPase activator activity. It is involved in the biological process described with: regulation of cell migration; regulation of GTPase activity; intracellular protein transport; regulation of protein localization; activation of GTPase activity. 12 alleles are reported. The phenotype of these alleles manifest in: border follicle cell. The phenotypic classes of alleles include: viable; fertile; cell migration defective.
Coordinates
chrX:11430523-11435481:-
Coord C1 exon
chrX:11435383-11435481
Coord A exon
chrX:11433418-11435382
Coord C2 exon
chrX:11430523-11433417
Length
1965 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
3' ss Seq
ATCTTTTCGATTTACTGCAGCTG
3' ss Score
8.02
Exon sequences
Seq C1 exon
AACTCGGAAATGCTCGCCGAGGGCGAACTGCGCGCGAATCTGGATGATTCGGACAAGGTGCGCGACCTGCAGGACAGGCTGGCCGACATGAAGGCGGAG
Seq A exon
GTGAGCGTGAGATGATCTGCAATGTTCACAGCATTTGTCGCTAATCCCCCACTGCTTTTGGTTTTGGTTTCGGTTTCGGTTTTAAGTTCATTCAAATGCCAGCAGCAGCAGACATTCAATAATAACACGTCCACCCACTCATTTTATGTCCACCCATCCAACTGACTAAACCAGAGGCCAGATCAGAGACACGTTTCCAATCTGGAGGAGCACGCTGTGGCCTCCTGTAGCGGATTTTCACTATAAATATGCTTTGTTTGCTAGCTGAGCGCAAGTCAAATCTGTTTGCTATGCTCACATTGCAAAATATATCGATTTGACTTGAAGTTACTAATTGAAAAAAGAAACCAAAGAATTTTTGAGTTTGCTGTGCTTTACTGTACACCCATTTTTAAATTGCTATTCAGGCATTTTATTGTACGTTTTGTTTTTAATTTTCGTTGGCTAATTTTAAAAACACATTCCGTAACCCATTTGCTGTAAGCCAAGATAATAATCTTGTATTTCTCATTGAATTTCTCTTTCACACGCAAAAAAAAAACAATGCGTTGTTGGTCTTGCTCCATAGTATCCCACGCCAATAACCAGCCCCGACACTGAGCCGTGGAAATGGATAAGCTAAACTAATTTTAACACCGCCCCCGAATACGAAAACACACGAAATTGATTGATAACGAAACAAAACGATCAAAATTATGAAAATTACAGAAAGAAAAAAAAGATTTAAAAGCAAATTACCGAAACCCAATTAGAAAATCAAGAAGCCACAATTATCCTCTAATCTTAATTGCCACAAACACACACACACACACACACTCAACTCCCGAAAACGTTAAAGAAATTCAAATGTCAAGCAGCAGGCCAAGCTACCAACTCTACCCAGGTCTCTATGAAACTGCTCAAAAACAACTCAGTACTTTTAACCAATTGCGTATTTGTAGCATTTGCTGTTGACCCTACCATCCCAACGTCCATAGTTTGTTCGCACGATTTGTAGTCCCATTTCCATAGTTTGAAAATGCATGAATGACCCCCCCCCAGTTAACCATTTTTGTATTGCTAGTTTTCGTAGTTCATTGCAAGTCGATTTCAGTAAGCCATATTCATTCACGCATAATAACGTTTAGAGCTCAAAACTATACTTTATAAAATAATATATTATTATTGTACCTTAATCGTGCTGCATAGTGTACATCTCTCCGAATTTTGAAAAAGAAGCTTTCTGCGAGCTTTGAGCTTGTACGCGAACCTTTATATGGAATACGTTCTAGTTCCGATCGATTCGATGTATATGACTTATTTCGACGTGGGTCAATGACTCCTACTCCTAATAGCATTCGTTTTAAGATTGACTTGACAATGGTGCCATGTGGAAGATTTCGGATTTGATTTTAATCGAAAGCCGCTGTTGTTTGTTTTGCATACTTGTAATGACGTATTGTAATCGTTGGTCTTGACATGGGAATGATGCTGTTTTGACACGAGTTCATTTCGACCTTGCTATGGATTATTTTTATTCGATTTTCAATTGAACTGTAGCTAGAAAATTGAGGGAGTGTTCTAGACCTATGATTTATAGAAATGCATATTGTAATATTATTAATTTTCTGCACGCTCGCATGCCTTCTTATCTAACACACACACTCACAGCACACTACTAATCAATAAGGTATTTAAGACACGTTCCACTACATGGACATTAAATAAGATTTATCTGTAGTCGGATCTATGTTACTTGTTTTCTAATTACTAGGTTAAAGCACTTAAGGCGGCTTTTCTTTTCAGTTTAGTGACACGTGGTATTATATATAAAAAAAGAAGTAAATATATCTATGTTTCAATCGCCGCATGATCAAAATTAGCAACTGCTTTAGCCTTGTAATCGTATTTTACACGTATTTATTTATAATTTATTTTCTTTTTTTAACGAACTACCAACTAATGAATCTTTTCGATTTACTGCAG
Seq C2 exon
CTGACGGCATTGAAAAGTCGTGGCAAATTTCCGGGCGCCAAACTGCGCAGCTCCTCGATCCAATCGATCGAATCGACCGAGATCGACTTCAATGATCTGAATATGGTGAGGCGCGGAAGTACGGAGCTCTCCACATAACCTACAGATGGATCAGATCTAGCATATCCAAACCAACCAACAGCCACAACCAGTAGAAAAGCAGCGAGTGAGAGGAAAGTACAGGATACACCCAAATCTAAATGGGTGGGCAAGCTGGAGGCGATTTATATATATTAATATATATATACATAGATGGATATACATATATATGAGGGGCCTGTGATTATGAAACGGAAAGGGAAGGTGGAGCATCGAGTGGAGGGAGAAGTAGAAGGAAGAGGGCAGAATAGTTGCAATCCCATTACAATATTAGTTATGTATAATATTCGTTAAAATTTTACTACTACTATTACGATATATGGATATTTTAGTACGATAATTATAAACTATATTTTTTTTTTTGCAATAATTTTATTACTGTTATGTTTTGCAATCGAAACACACTCATATTTATTTATTTTAAATCCTAATTGAAACGATATTGTGAGAGTATTTTACACCCCTGTACATTAATCAATACGGCAACTAATCCGATTCGATGCGATGCGATGGATTGGAGTTAGGAGATTGGCATTTTGATATACCCTAGATGTATGGCACATATGCAATGCAATGAATTTTATGTAAACCCCTGAGGAAAAAACAAAACCATTTCCCAACCCAGGCATCCTGTGAACCACTTTTAATGTAAGTTTTAAGCGAATCCGAAATTGTTCTTGGCTACAAACAAAACAAAAAAAAAAAAAAAAACGATTTTAATCAGCACGCACACCTTTTTAAAGTGTGCGGATAATGCTTGGTTTATCCACTTGATTTGTATTATGATTTCATCCCTGTAGAATGATATTAACACTCACAAACACACAGTTGTCTGGAATGAATTTTGTAACTCTCGTATAGTAAGCTAAACCAATCTAAATCTAAAACGATAACTAAAATAAAACCAAGTGCGAAAGACAAAGTAACATGCGTGGCCAAATGCAAGATGAGAAACTGAGAAACCAATATATAACTATTAAAAATAGTTTAAAACGATATGTGAAAGAACCACGAGAAAAGGGGCCCACAATTTATCCCCGTTTAAGAACGATATTACGATAACGACTACGATATTCACACTACTTACGATATTCTACTTAGTTAACAGTAGCGCTTATCTTTATCCACAAAAACAAAGAAAATACAATTATATGATTTATATGGTTCATTTAACCCATATTTGGCAGCTTGTCGCGTAAAACGATTTCGATTTTGACATCGACTTTCGAAACGATTAACAATAATTATCCACAAACATTACAATTATTCAGGTTGAACCATGTTTTCCATGTGCAATATTATACATTTACTTTCGCTTCTATTGCGTTTCGTATTCTATGACAATTTTTTATTATCATTTGTTAGTATGACGTCCTCAGTGCTTAGGTTTGTTACTTATCGCAACTAAGACCGATTAACTTAATTAACTTAATTTTTGTAATTCCATTGATTTGCCCATCATGACAAACCGATTAAAAAACAGCAAGAGAAATAAGAGAGATCTATGTAATAGGATTCGTAGCTTGTAAGAATGTCGAAAATGATGTCACAAAACTTTGTTATGTAAACACTAAGTATATATGTAATGCTTAAGTTTTGTTCTCGACTTTGGCAGAACTATTAGAATTTTTTGTTCTACGCGATAATTAATGATTATGATTATGTAATGTATGTGTTATATATAACATATAAAATGATATGTTTGCGGCTAAAAGAGGAGGCTGCTGGGGGAGGGGCAGTATTAACAATCAGCAGGAGTTAACAGACATTTAAATATAGCAAACATTCCCGAGAACGTCAAATTTCCCCCAAGAAATGAAAAGATAAGCAAATTCCCCCAACAGCCTCGAGTCTTAAAAAATTGGCAAGTCTAGAGTTAATTGCGTATTATGTTATGGCAAGCGAAGGCACAAATTATACGATATCTAAAATAGTTTATACAAATTTATACACGCAAATGGAGAGCATCATTGTTGGCCAAAGTCTAGACTTGGCCCGCGCATAGTTCGGTGTTAACTGATTGACCAATAAGTGTGGAACTCGTGCGAATTGCCGTTCAAACAACTGGCCCCCAGCCCCACTTAAGTGACTCACCGGGGCGGTAGTATAATGAACCCCATCGTCGATAGCAGCTAATTTCAATGCCCTGCCCTGTCAGTTCGATTTGATAAATGTGAAAATGTGAAAAGAAAGACTCTTGGCGTTTATCAATTCAGCATGTGAATGCGAATGCCAACGACTTTGGGCCCAGACAGAAGGCAGACGGTAACGATTTGTTGACCTTGGACGGCGAGAACGATCGAAACTCCTTTGAACGCAATTAATTAGCGGGCAAACTCGCTCATAGCGTATACTTAATACAAATAAATCAAGTTCAGCTTCCATTGAGCAAGACTCTACAGTCAACAGTCTAATAGTCTTCAGTGTTTAATGTGTTCTGTGTTCATCTTGATTTGCACTTATTGATTGCGTTTCTCGTTTCATTCATTGTTGATCCATTGAACAAAGCCAGGCGACAAAATTAAAAAAAAAAAAAGTCACAAGAACTAGAAAGTAGTTGACAAAATACCACAACAAATAGTGTTATATACTTTACATATACCTAACTATATCAATATAACGATAAAACTGATAACTGAAGAGCAGAAAGAAGTAAAATTCAACTAAAACTACAACAAATCAATAAAATTAAACGGATATACAAAACGAAATCAAAGTTACAATTTTTAGTATTAAATAAATGAAAAGAAAACCAAC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0262740:FBtr0073547:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.929 A=NA C2=0.311
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0073392
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0289957
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACTCGGAAATGCTCGCCG
R:
CAGCTTGCCCACCCATTTAGA
Band lengths:
354-2319
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)