DmeEX0004321 @ dm6
Exon Skipping
Gene
FBgn0262740 | Evi5
Description
The gene Ecotropic viral integration site 5 is referred to in FlyBase by the symbol DmelEvi5 (CG11727, FBgn0262740). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is X:11430523..11454386. Its molecular function is described by: Rab GTPase binding; GTPase activator activity. It is involved in the biological process described with: regulation of cell migration; regulation of GTPase activity; intracellular protein transport; regulation of protein localization; activation of GTPase activity. 12 alleles are reported. The phenotype of these alleles manifest in: border follicle cell. The phenotypic classes of alleles include: viable; fertile; cell migration defective.
Coordinates
chrX:11430523-11435481:-
Coord C1 exon
chrX:11435383-11435481
Coord A exon
chrX:11434500-11434814
Coord C2 exon
chrX:11430523-11433417
Length
315 bp
Sequences
Splice sites
3' ss Seq
TTGTTGGTCTTGCTCCATAGTAT
3' ss Score
7.43
5' ss Seq
CAGGTCTCT
5' ss Score
1.07
Exon sequences
Seq C1 exon
AACTCGGAAATGCTCGCCGAGGGCGAACTGCGCGCGAATCTGGATGATTCGGACAAGGTGCGCGACCTGCAGGACAGGCTGGCCGACATGAAGGCGGAG
Seq A exon
TATCCCACGCCAATAACCAGCCCCGACACTGAGCCGTGGAAATGGATAAGCTAAACTAATTTTAACACCGCCCCCGAATACGAAAACACACGAAATTGATTGATAACGAAACAAAACGATCAAAATTATGAAAATTACAGAAAGAAAAAAAAGATTTAAAAGCAAATTACCGAAACCCAATTAGAAAATCAAGAAGCCACAATTATCCTCTAATCTTAATTGCCACAAACACACACACACACACACACTCAACTCCCGAAAACGTTAAAGAAATTCAAATGTCAAGCAGCAGGCCAAGCTACCAACTCTACCCAG
Seq C2 exon
CTGACGGCATTGAAAAGTCGTGGCAAATTTCCGGGCGCCAAACTGCGCAGCTCCTCGATCCAATCGATCGAATCGACCGAGATCGACTTCAATGATCTGAATATGGTGAGGCGCGGAAGTACGGAGCTCTCCACATAACCTACAGATGGATCAGATCTAGCATATCCAAACCAACCAACAGCCACAACCAGTAGAAAAGCAGCGAGTGAGAGGAAAGTACAGGATACACCCAAATCTAAATGGGTGGGCAAGCTGGAGGCGATTTATATATATTAATATATATATACATAGATGGATATACATATATATGAGGGGCCTGTGATTATGAAACGGAAAGGGAAGGTGGAGCATCGAGTGGAGGGAGAAGTAGAAGGAAGAGGGCAGAATAGTTGCAATCCCATTACAATATTAGTTATGTATAATATTCGTTAAAATTTTACTACTACTATTACGATATATGGATATTTTAGTACGATAATTATAAACTATATTTTTTTTTT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0262740_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.929 A=0.882 C2=0.311
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0304866
Main Skipping Isoform:
FBpp0073392
Other Inclusion Isoforms:
FBpp0073391, FBpp0289956
Other Skipping Isoforms:
FBpp0289957
Associated events
Conservation
Human
(hg19)
No conservation detected
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACTCGGAAATGCTCGCCG
R:
CAGCTTGCCCACCCATTTAGA
Band lengths:
354-669
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)