DmeINT0024826 @ dm6
Intron Retention
Gene
FBgn0263197 | Patronin
Description
The gene Patronin is referred to in FlyBase by the symbol DmelPatronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 14 annotated transcripts and 14 polypeptides (13 unique). Gene sequence location is 2R:17519024..17535866. Its molecular function is described by: microtubule minus-end binding; spectrin binding; calmodulin binding; microtubule binding. It is involved in the biological process described with 6 unique terms, many of which group under: developmental process; cytoskeleton organization; negative regulation of cellular process; plasma membrane bounded cell projection organization; microtubule-based process. 36 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; intracellular non-membrane-bounded organelle; cytoskeleton; organelle; plasma membrane bounded cell projection. The phenotypic classes of alleles include: viable; size defective; increased mortality; phenotype.
Coordinates
chr2R:17528622-17529191:-
Coord C1 exon
chr2R:17529087-17529191
Coord A exon
chr2R:17528853-17529086
Coord C2 exon
chr2R:17528622-17528852
Length
234 bp
Sequences
Splice sites
5' ss Seq
AAGGTAATT
5' ss Score
8.83
3' ss Seq
CGCTGCCCGTCAACCTGCAGCCT
3' ss Score
7.75
Exon sequences
Seq C1 exon
TTCCGCACTCGAATTCATTTGGCGGCGGCTTAAATCGCAGATCAACCCCGCCCAACGAATACCAGACGGTTCAGTCAAATAATTTTGACGGTAATCATGCCGAAG
Seq A exon
GTAATTTATTTATTATTATTACTTAATTACTTTAATTATTTCTCTCTACCTTTTATTTTCATTAATTTTTGTGTACGTTTCTGTTTGCTCTTTATTTGCACTCAGAAACTGCAACTCAATGTCTTATTGGTTTCTGATTGAATTTAAATTTTGTAACTTTTTCTTTTCACCACCCACCGACCCACACACGCTTAACCACCAACCACAACGCCACCGCTGCCCGTCAACCTGCAG
Seq C2 exon
CCTTCGTGGTGCACAAGTCGCGTGGCATCACCACACTCGCCTCCATGCACTCGCAGCAGCAGCAGCAGCTCCATCAGCAGCAACAGCATCAGCAGCAATACCATCAGCAGCCACTGCAGCAGCACCCGTCCCAGTCGCAGCTTCAAATCCAACAGCAGGAGCCCTTGGTTCCAGCTCGCTTGCGCCAGGCTAAAGAAAAGACCAATGTTGAGTCGAAGGCGGACGAGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0263197:FBtr0086948:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.852 A=NA C2=0.904
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0304550
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0086104, FBpp0086105, FBpp0086106, FBpp0271954, FBpp0271955, FBpp0289830, FBpp0304551, FBpp0304556
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCACTCGAATTCATTTGGCG
R:
TCTTTTCTTTAGCCTGGCGCA
Band lengths:
303-537
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)