DmeINT0032123 @ dm6
Intron Retention
Gene
FBgn0001083 | fw
Description
The gene furrowed is referred to in FlyBase by the symbol Dmelfw (CG1500, FBgn0001083). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:11992915..12003914. Its molecular function is described by: carbohydrate binding. It is involved in the biological process described with 6 unique terms, many of which group under: biological regulation; cell-cell adhesion via plasma-membrane adhesion molecules; eye morphogenesis; regulation of biological quality; homophilic cell adhesion via plasma membrane adhesion molecules. 38 alleles are reported. The phenotypes of these alleles manifest in: sensory system neuron; pupal spiracle; ovary; excretory system; epithelial cell. The phenotypic classes of alleles include: fertile; increased mortality; phenotype; visible. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during late pupal stages.
Coordinates
chrX:11996392-11996790:-
Coord C1 exon
chrX:11996641-11996790
Coord A exon
chrX:11996569-11996640
Coord C2 exon
chrX:11996392-11996568
Length
72 bp
Sequences
Splice sites
5' ss Seq
ACTGTAGGT
5' ss Score
4.15
3' ss Seq
TCTTTACCATCTTCCGGCAGCGC
3' ss Score
8.36
Exon sequences
Seq C1 exon
GCGATGTGGTTCAAAAGCCAACATGGGGCAAGGACCAGCCGAACAACTACAATGGCGAGCAGAATTGCGTGGTCCTCGATGGAGGTCGCAATTGGCTGTGGAATGATGTGGGCTGCAATCTGGACTATTTGCACTTCATCTGCCAGCACT
Seq A exon
GTAGGTCTTGCCAGTGCCATCGGCACATCACCAGCTCGTCTCATTTTGTCTCTCTTTACCATCTTCCGGCAG
Seq C2 exon
CGCCATTGTCTTGCGGCTCGCCGGATGCCCAGCAAAACACCACTGTCATGGGCAAAAAGTTCACTCTGGGCGAGAAGATTCAGTACACCTGTCCCAAGGGCCATTCGCTGCTCGGTCAGACGGAACGGGAGTGTAGACTTGATGGCACTTGGAGTGGCTCCTCGCCGACCTGCAAAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0001083:FBtr0073580:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.078 A=NA C2=0.037
Domain overlap (PFAM):
C1:
PF0005916=Lectin_C=PD(42.2=96.1)
A:
NA
C2:
PF0008415=Sushi=WD(100=90.0),PF0279317=HRM=PU(86.8=76.7)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
FBpp0073424

Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0111718, FBpp0309601
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAATTGCGTGGTCCTCGATG
R:
TCTTCTCGCCCAGAGTGAACT
Band lengths:
168-240
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)