DmeINT0036134 @ dm6
Intron Retention
Gene
FBgn0041096 | rols
Description
The gene rolling pebbles is referred to in FlyBase by the symbol Dmel
ols (CG32096, FBgn0041096). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (7 unique). Gene sequence location is 3L:12008225..12064859. Its molecular function is described by: cell adhesion molecule binding; structural constituent of muscle; protein binding. It is involved in the biological process described with: myoblast fusion; border follicle cell migration; anterior Malpighian tubule development; sarcomere organization. 49 alleles are reported. The phenotypes of these alleles manifest in: larva; dorsal closure embryo; embryonic/larval digestive system; nervous system; somatic muscle primordium. The phenotypic classes of alleles include: increased mortality during development; phenotype; fertile; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.
Coordinates
chr3L:12055194-12056474:-
Coord C1 exon
chr3L:12056230-12056474
Coord A exon
chr3L:12055709-12056229
Coord C2 exon
chr3L:12055194-12055708
Length
521 bp
Sequences
Splice sites
5' ss Seq
AAAGTAATA
5' ss Score
0.92
3' ss Seq
GTTTTTCTCGTTTTGTAAAGCGC
3' ss Score
5.99
Exon sequences
Seq C1 exon
GCTCAGTTTCGAAACGAACTTCAAAGCTCGCGCAAGCGTACCGCACGCGAATCGGAAAACGCATTCTACGATCGGCAAATCATCGCGATACACGATCTTTCTTCAGCCGGCATTTTCTTGTTCGCCACTCTGGATACGGTTTCAAATCGCAAAACGTGCCAAGTTCCTTAAAAAGTGTGCGAAAATTGCAAATATTTTGAGTTTCCATGTGACGTATGCGTAATGTGACCACAGTGCGGATTAAA
Seq A exon
GTAATATATTTACCTGTATATAAATGCGACTATATATATGCGTGTGTGTGTGTGTCATTGTCTAGGAATTTTGTTTCGTCTGCAAAATGTGCAAAGTTTTTTAATGTTTACATCGCGAAATTCCAAGAGTCCCAGTTGACTCACGATTAAGACAAAAAGAGATTAGATAAAGAGTGACCAACTTATCTATACATTGGTGTTCACCTTAGTTTCGCAAATTTATGAAAATGTTTTGATTTGAGATTATAAGGCTTAAAAAATCGAATACAACGTTGACTTAATTTGAAATCTAGGCTCTTAAAACTGAAGATTGATCTAACAAATTATTGTTTTGCTTTAAAAGCTTAAAATATTATTCGACAGGTGTAAATGTGACAAATCCAATTAGTAAACAAGTAATTCTCTTTGCACAAAAACGCAGAAAACTAAACAAAAACCTACACAAACTACATTGGTCGTAATGTGTGAAGAAATTAAAAATTATAAATTTAAATAAGTGTGGTTTTTCTCGTTTTGTAAAG
Seq C2 exon
CGCTCTTTAGATGTATTTCGAAAACGAATTTAACGAATAGGTGTAAAGGAAAAATCCACAAAAGTACGTGCCACCAAAAAGTGCAAAAGAAGGGCAAATCGAACGAGAAATTCGGCTCGAAAAGCTGGACAAAATCGACTTGAAAGGATTCGCAGCTGGAACTGCATCCATCCAGATACAGATCCAGATACATGTGTATATACCGTATACCAGTGCCGATACAGATACAGATACATACATACATGAGGCAGCCTGCGAACCACAAAAGATACATGCCATGTTCCCACTAACCAACCGCTCTTCGAGTGGCAATCGCACCAACAACAATCCGAGCAACAACAACAACAACCAGACCACAAGCTTCATAATCGGAGGTACCACCAATATTAACAACAACAACAATCAGCTTGGTGGCACAAACAGCGCTAAGGATAAAGGAAATTTTGAAAATAATTGGAGCTGCAATAAAACAACCGGTCGTCGATCTGGCAGTGGAAATAGTTGCAGTTTTTTAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0041096:FBtr0076056:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=0.637 A=NA C2=0.637
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
FBpp0075786
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0075789
Other Skipping Isoforms:
FBpp0075787, FBpp0075788, FBpp0301715, FBpp0306229
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGCATTCTACGATCGGCAAA
R:
CAGTTCCAGCTGCGAATCCTT
Band lengths:
351-872
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)